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CAZyme Information: MGYG000000013_00446

You are here: Home > Sequence: MGYG000000013_00446

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Bacteroides sp902362375
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides sp902362375
CAZyme ID MGYG000000013_00446
CAZy Family GT6
CAZyme Description O-antigen biosynthesis glycosyltransferase WbnI
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
263 30895.37 6.822
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000013 6368149 Isolate United Kingdom Europe
Gene Location Start: 617352;  End: 618143  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000013_00446.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT6 2 220 3.4e-75 0.7714285714285715

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd02515 Glyco_transf_6 9.11e-47 2 214 35 245
Glycosyltransferase family 6 comprises enzymes responsible for the production of the human ABO blood group antigens. Glycosyltransferase family 6, GT_6, comprises enzymes with three known activities: alpha-1,3-galactosyltransferase, alpha-1,3 N-acetylgalactosaminyltransferase, and alpha-galactosyltransferase. UDP-galactose:beta-galactosyl alpha-1,3-galactosyltransferase (alpha3GT) catalyzes the transfer of galactose from UDP-alpha-d-galactose into an alpha-1,3 linkage with beta-galactosyl groups in glycoconjugates. The enzyme exists in most mammalian species but is absent from humans, apes, and old world monkeys as a result of the mutational inactivation of the gene. The alpha-1,3 N-acetylgalactosaminyltransferase and alpha-galactosyltransferase are responsible for the production of the human ABO blood group antigens. A N-acetylgalactosaminyltransferases use a UDP-GalNAc donor to convert the H-antigen acceptor to the A antigen, whereas a galactosyltransferase uses a UDP-galactose donor to convert the H-antigen acceptor to the B antigen. Alpha-1,3 N-acetylgalactosaminyltransferase and alpha-galactosyltransferase differ only in the identity of four critical amino acid residues.
pfam03414 Glyco_transf_6 2.51e-42 3 216 53 264
Glycosyltransferase family 6.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QDH53874.1 1.16e-203 1 263 1 263
QRM99205.1 1.16e-203 1 263 1 263
QUT26666.1 1.04e-196 1 254 1 254
QUT78828.1 2.81e-186 1 263 1 263
ALJ48119.1 2.81e-186 1 263 1 263

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4AYJ_A 1.28e-177 1 246 1 246
Molecularstructure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen [Bacteroides ovatus],4AYJ_B Molecular structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen [Bacteroides ovatus],4AYJ_C Molecular structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen [Bacteroides ovatus],4AYJ_D Molecular structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen [Bacteroides ovatus],4AYL_A Molecular structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen [Bacteroides ovatus]
4CJB_A 3.66e-177 1 246 1 246
orthorhombiccrystal form of Bogt6a E192Q in complex with GalNAc [Bacteroides ovatus],4CJB_B orthorhombic crystal form of Bogt6a E192Q in complex with GalNAc [Bacteroides ovatus],4CJB_C orthorhombic crystal form of Bogt6a E192Q in complex with GalNAc [Bacteroides ovatus],4CJB_D orthorhombic crystal form of Bogt6a E192Q in complex with GalNAc [Bacteroides ovatus],4CJC_A orthorhombic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP, GalNAc [Bacteroides ovatus],4CJC_B orthorhombic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP, GalNAc [Bacteroides ovatus],4CJC_C orthorhombic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP, GalNAc [Bacteroides ovatus],4CJC_D orthorhombic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP, GalNAc [Bacteroides ovatus]
4CJ8_A 3.94e-177 1 246 3 248
monocliniccrystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_B monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_C monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_D monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_E monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_F monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_G monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_H monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_I monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_J monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_K monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_L monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_M monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_N monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_O monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus],4CJ8_P monoclinic crystal form of Bogt6a E192Q in complex with UDP-GalNAc, UDP and GalNAc [Bacteroides ovatus]
1R7T_A 2.72e-31 3 218 54 270
GlycosyltransferaseA in complex with 3-deoxy-acceptor analog inhibitor [Homo sapiens],1R7V_A Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor [Homo sapiens],1R7Y_A Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate [Homo sapiens],1R81_A Glycosyltransferase A in complex with 3-amino-acceptor analog inhibitor and uridine diphosphate-N-acetyl-galactose [Homo sapiens]
1LZ0_A 3.29e-31 3 218 54 270
GlycosyltransferaseA [Homo sapiens],1LZI_A Glycosyltransferase A + UDP + H antigen acceptor [Homo sapiens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q5ZLK4 3.58e-37 1 235 105 340
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 OS=Gallus gallus OX=9031 GN=GBGT1 PE=2 SV=1
Q5JBG6 2.51e-35 1 239 1 231
O-antigen biosynthesis glycosyltransferase WbnI OS=Escherichia coli OX=562 GN=wbnI PE=1 SV=1
P38649 3.52e-33 3 218 95 311
Histo-blood group ABO system transferase OS=Mus musculus OX=10090 GN=Abo PE=1 SV=2
Q9ET32 9.33e-33 3 218 111 327
Histo-blood group ABO system transferase 1 OS=Rattus norvegicus OX=10116 GN=Abo PE=1 SV=1
Q95158 5.01e-31 1 214 109 320
Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 OS=Canis lupus familiaris OX=9615 GN=GBGT1 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000032 0.000001 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000013_00446.