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CAZyme Information: MGYG000000042_00357
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Phocaeicola sp900066445 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Phocaeicola; Phocaeicola sp900066445 | |||||||||||
| CAZyme ID | MGYG000000042_00357 | |||||||||||
| CAZy Family | PL6 | |||||||||||
| CAZyme Description | Chondroitinase-B | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 398631; End: 400091 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| PL6 | 22 | 408 | 1.7e-92 | 0.9865591397849462 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam14592 | Chondroitinas_B | 9.21e-119 | 24 | 447 | 1 | 426 | Chondroitinase B. This family includes chondroitinases. These enzymes cleave the glycosaminoglycan dermatan sulfate. |
| cd14251 | PL-6 | 2.81e-94 | 24 | 409 | 1 | 368 | Polysaccharide Lyase Family 6. Polysaccharide Lyase Family 6 is a family of beta-helical polysaccharide lyases. Members include alginate lyase (EC 4.2.2.3) and chondroitinase B (EC 4.2.2.19). Chondroitinase B is an enzyme that only cleaves the beta-(1,4)-linkage of dermatan sulfate (DS), leading to 4,5-unsaturated dermatan sulfate disaccharides as the product. DS is a highly sulfated, unbranched polysaccharide belonging to a family of glycosaminoglycans (GAGs) composed of alternating hexosamine (gluco- or galactosamine) and uronic acid (D-glucuronic or L-iduronic acid) moieties. DS contains alternating 1,4-beta-D-galactosamine (GalNac) and 1,3-alpha-L-iduronic acid units. The related chondroitin sulfate (CS) contains alternating GalNac and 1,3-beta-D-glucuronic acid units. Alginate lyases (known as either mannuronate (EC 4.2.2.3) or guluronate lyases (EC 4.2.2.11) catalyze the degradation of alginate, a copolymer of alpha-L-guluronate and its C5 epimer beta-D-mannuronate. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ADY54336.1 | 8.50e-158 | 11 | 486 | 13 | 496 |
| AAC83384.1 | 3.00e-146 | 24 | 481 | 28 | 485 |
| ABJ38857.1 | 3.00e-146 | 24 | 481 | 28 | 485 |
| ACK03140.1 | 3.00e-146 | 24 | 481 | 28 | 485 |
| ACU03011.1 | 3.00e-146 | 24 | 481 | 28 | 485 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7O78_A | 7.34e-158 | 20 | 486 | 2 | 476 | ChainA, Polysaccharide lyase from Pseudopedobacter saltans, Pedsa3807 [Pseudopedobacter saltans DSM 12145],7O78_B Chain B, Polysaccharide lyase from Pseudopedobacter saltans, Pedsa3807 [Pseudopedobacter saltans DSM 12145] |
| 1OFL_A | 4.83e-148 | 24 | 481 | 3 | 460 | CRYSTALSTRUCTURE OF CHONDROITINASE B COMPLEXED TO DERMATAN SULFATE HEXASACCHARIDE [Pedobacter heparinus],1OFM_A CRYSTAL STRUCTURE OF CHONDROITINASE B COMPLEXED TO CHONDROITIN 4-SULFATE TETRASACCHARIDE [Pedobacter heparinus] |
| 1DBG_A | 1.10e-147 | 24 | 481 | 28 | 485 | CRYSTALSTRUCTURE OF CHONDROITINASE B [Pedobacter heparinus],1DBO_A Crystal Structure Of Chondroitinase B [Pedobacter heparinus] |
| 7O79_A | 6.21e-32 | 21 | 470 | 2 | 454 | ChainA, Poly(Beta-D-mannuronate) lyase [Pseudopedobacter saltans DSM 12145] |
| 7O77_A | 6.41e-32 | 32 | 479 | 12 | 431 | ChainA, Poly(Beta-D-mannuronate) lyase [Pseudoalteromonas atlantica T6c] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q46079 | 6.01e-147 | 24 | 481 | 28 | 485 | Chondroitinase-B OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=cslB PE=1 SV=2 |
| Q06365 | 9.20e-22 | 39 | 380 | 2 | 322 | Alginate lyase OS=Pseudomonas sp. (strain OS-ALG-9) OX=86038 GN=aly PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000483 | 0.535495 | 0.463444 | 0.000223 | 0.000196 | 0.000168 |