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CAZyme Information: MGYG000000046_01582

You are here: Home > Sequence: MGYG000000046_01582

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Megasphaera stantonii
Lineage Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Megasphaeraceae; Megasphaera; Megasphaera stantonii
CAZyme ID MGYG000000046_01582
CAZy Family GT83
CAZyme Description Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
537 MGYG000000046_13|CGC1 60877.91 9.3587
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000046 2558124 Isolate United Kingdom Europe
Gene Location Start: 31629;  End: 33242  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000046_01582.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT83 4 459 4.8e-86 0.8759259259259259

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1807 ArnT 4.45e-41 4 421 7 431
4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis].
PRK13279 arnT 1.18e-25 1 389 2 395
lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase.
pfam13231 PMT_2 1.62e-13 60 219 1 157
Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.
pfam02366 PMT 2.03e-08 32 193 32 200
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.
COG4745 COG4745 1.13e-04 46 335 46 382
Predicted membrane-bound mannosyltransferase [General function prediction only].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AXL21032.1 0.0 1 537 1 537
AXB83023.1 2.19e-228 1 536 1 536
ALG41393.1 5.23e-228 1 534 1 532
CCC72525.1 7.42e-228 1 534 1 532
AVO73980.1 7.42e-228 1 534 1 532

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5EZM_A 1.33e-22 27 337 54 374
CrystalStructure of ArnT from Cupriavidus metallidurans in the apo state [Cupriavidus metallidurans CH34],5F15_A Crystal Structure of ArnT from Cupriavidus metallidurans bound to Undecaprenyl phosphate [Cupriavidus metallidurans CH34]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
B2VBI7 2.04e-23 1 311 1 316
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Erwinia tasmaniensis (strain DSM 17950 / CFBP 7177 / CIP 109463 / NCPPB 4357 / Et1/99) OX=465817 GN=arnT PE=3 SV=1
A1JPM4 2.75e-23 17 337 20 344
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) OX=393305 GN=arnT PE=3 SV=1
A6V1N8 1.16e-21 1 338 1 343
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Pseudomonas aeruginosa (strain PA7) OX=381754 GN=arnT PE=3 SV=1
B7LM74 2.78e-21 4 338 5 343
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CCUG 18766 / IAM 14443 / JCM 21226 / LMG 7866 / NBRC 102419 / NCTC 12128 / CDC 0568-73) OX=585054 GN=arnT PE=3 SV=2
A8GDR9 2.82e-21 9 341 11 348
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Serratia proteamaculans (strain 568) OX=399741 GN=arnT PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.159438 0.834932 0.002530 0.000950 0.000760 0.001360

TMHMM  Annotations      download full data without filtering help

start end
5 27
54 76
81 103
108 130
137 154
169 191
203 225
256 278
287 304
308 325
338 360
364 386
393 415