logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000000104_02842

You are here: Home > Sequence: MGYG000000104_02842

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Clostridium cuniculi
Lineage Bacteria; Firmicutes_A; Clostridia; Clostridiales; Clostridiaceae; Clostridium; Clostridium cuniculi
CAZyme ID MGYG000000104_02842
CAZy Family GT11
CAZyme Description O-antigen biosynthesis glycosyltransferase WbnK
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
286 MGYG000000104_24|CGC3 33897.6 7.7636
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000104 3679160 Isolate Canada North America
Gene Location Start: 22771;  End: 23631  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000104_02842.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT11 1 282 1.9e-76 0.9927536231884058

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd11301 Fut1_Fut2_like 1.92e-69 1 271 1 260
Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.
pfam01531 Glyco_transf_11 7.81e-31 1 268 32 280
Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes.
cd11548 NodZ_like 0.003 1 248 1 276
Alpha 1,6-fucosyltransferase similar to Bradyrhizobium NodZ. Bradyrhizobium NodZ is an alpha 1,6-fucosyltransferase involved in the biosynthesis of the nodulation factor, a lipo-chitooligosaccharide formed by three-to-six beta-1,4-linked N-acetyl-d-glucosamine (GlcNAc) residues and a fatty acid acyl group attached to the nitrogen atom at the non-reducing end. NodZ transfers L-fucose from the GDP-beta-L-fucose donor to the reducing residue of the chitin oligosaccharide backbone, before the attachment of a fatty acid group. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
SNX52916.1 3.03e-99 1 283 1 287
QTL97698.1 1.83e-85 1 285 1 276
AIT08976.1 6.65e-79 1 283 1 280
AUR51583.1 1.19e-76 1 283 1 279
AJI74371.1 2.33e-74 1 283 1 281

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q58YV9 4.44e-40 6 283 5 302
O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1
Q9TTC7 3.23e-12 4 286 66 336
Galactoside alpha-(1,2)-fucosyltransferase 2 OS=Hylobates lar OX=9580 GN=FUT2 PE=3 SV=1
P19526 1.19e-11 152 286 215 355
Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Homo sapiens OX=9606 GN=FUT1 PE=1 SV=1
Q9TUD6 1.20e-11 152 286 216 356
Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Pan troglodytes OX=9598 GN=FUT1 PE=3 SV=1
Q9TUD4 1.20e-11 152 286 216 356
Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Gorilla gorilla gorilla OX=9595 GN=FUT1 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000056 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000104_02842.