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CAZyme Information: MGYG000000122_02440

You are here: Home > Sequence: MGYG000000122_02440

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Staphylococcus epidermidis
Lineage Bacteria; Firmicutes; Bacilli; Staphylococcales; Staphylococcaceae; Staphylococcus; Staphylococcus epidermidis
CAZyme ID MGYG000000122_02440
CAZy Family GH23
CAZyme Description putative transglycosylase IsaA
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
235 MGYG000000122_24|CGC1 24577.37 6.2123
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000122 2560588 Isolate Canada North America
Gene Location Start: 3000;  End: 3707  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000122_02440.

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd13925 RPF 5.00e-06 176 234 1 69
core lysozyme-like domain of resuscitation-promoting factor proteins. Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF.
cd00254 LT-like 0.002 181 210 7 36
lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QRJ43786.1 2.17e-135 1 235 1 235
AIR81872.1 2.17e-135 1 235 1 235
AVG08193.1 2.17e-135 1 235 1 235
QHG30938.1 2.17e-135 1 235 1 235
QRL30458.1 2.17e-135 1 235 1 235

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q8CMZ9 4.33e-136 1 235 1 235
Probable transglycosylase IsaA OS=Staphylococcus epidermidis (strain ATCC 12228 / FDA PCI 1200) OX=176280 GN=isaA PE=3 SV=1
Q5HL49 4.33e-136 1 235 1 235
Probable transglycosylase IsaA OS=Staphylococcus epidermidis (strain ATCC 35984 / RP62A) OX=176279 GN=isaA PE=3 SV=1
Q2YWD9 1.00e-77 1 234 1 232
Probable transglycosylase IsaA OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) OX=273036 GN=isaA PE=3 SV=1
Q6G6A5 2.32e-76 1 234 1 232
Probable transglycosylase IsaA OS=Staphylococcus aureus (strain MSSA476) OX=282459 GN=isaA PE=3 SV=1
Q2FDT8 2.32e-76 1 234 1 232
Probable transglycosylase IsaA OS=Staphylococcus aureus (strain USA300) OX=367830 GN=isaA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000292 0.998955 0.000197 0.000208 0.000179 0.000159

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000122_02440.