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CAZyme Information: MGYG000000129_00529

You are here: Home > Sequence: MGYG000000129_00529

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Marseille-P4683 sp900232885
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; Marseille-P4683; Marseille-P4683 sp900232885
CAZyme ID MGYG000000129_00529
CAZy Family PL8
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
2118 234743.99 4.1533
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000129 2720267 Isolate Canada North America
Gene Location Start: 159537;  End: 165893  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000129_00529.

CAZyme Signature Domains help

Family Start End Evalue family coverage
PL8 430 683 2e-72 0.9806949806949807
CBM32 1289 1403 5.8e-27 0.9516129032258065
CBM32 1425 1541 5.8e-24 0.9435483870967742

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd01083 GAG_Lyase 2.91e-159 34 757 1 692
Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase.
pfam02278 Lyase_8 8.10e-73 428 682 2 252
Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam08124 Lyase_8_N 1.81e-58 42 378 1 322
Polysaccharide lyase family 8, N terminal alpha-helical domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.
pfam00754 F5_F8_type_C 1.01e-18 1292 1399 4 121
F5/8 type C domain. This domain is also known as the discoidin (DS) domain family.
pfam02884 Lyase_8_C 6.22e-17 698 766 1 67
Polysaccharide lyase family 8, C-terminal beta-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
BCI59535.1 0.0 1 2118 1 2118
QOX65559.1 0.0 2 1797 8 1796
QMV41282.1 0.0 2 1656 3 1652
ALC80364.1 1.32e-145 12 808 13 782
QIZ07197.1 8.12e-145 12 948 12 936

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6F2P_A 5.80e-132 33 813 4 752
Structureof Paenibacillus xanthan lyase to 2.6 A resolution [Paenibacillus]
1J0M_A 2.73e-112 33 809 2 748
CrystalStructure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1],1J0N_A Crystal Structure of Bacillus sp. GL1 Xanthan Lyase that Acts on Side Chains of Xanthan [Bacillus sp. GL1]
2E22_A 3.71e-112 33 809 2 748
Crystalstructure of xanthan lyase in complex with mannose [Bacillus sp. GL1]
2E24_A 3.71e-112 33 809 2 748
ChainA, Xanthan lyase [Bacillus sp. GL1]
1X1H_A 4.25e-111 33 809 2 748
ChainA, xanthan lyase [Bacillus sp. GL1],1X1I_A Chain A, xanthan lyase [Bacillus sp. GL1],1X1J_A Chain A, xanthan lyase [Bacillus sp. GL1]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q9AQS0 6.40e-112 33 910 27 881
Xanthan lyase OS=Bacillus sp. (strain GL1) OX=84635 GN=xly PE=1 SV=1
Q59801 6.58e-61 31 780 46 792
Hyaluronate lyase OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=hysA PE=3 SV=1
Q53591 3.17e-53 19 711 236 929
Hyaluronate lyase OS=Streptococcus agalactiae serotype III (strain NEM316) OX=211110 GN=hylB PE=1 SV=2
Q54873 9.61e-50 42 708 298 945
Hyaluronate lyase OS=Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) OX=170187 GN=SP_0314 PE=1 SV=2
P0CZ01 8.47e-45 114 818 109 804
Hyaluronate lyase OS=Cutibacterium acnes (strain DSM 16379 / KPA171202) OX=267747 GN=PPA0380 PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000315 0.998955 0.000176 0.000199 0.000169 0.000153

TMHMM  Annotations      download full data without filtering help

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