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CAZyme Information: MGYG000000196_01557
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Bacteroides thetaiotaomicron | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; Bacteroides thetaiotaomicron | |||||||||||
| CAZyme ID | MGYG000000196_01557 | |||||||||||
| CAZy Family | GH137 | |||||||||||
| CAZyme Description | Beta-galactosidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 226663; End: 230946 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH137 | 27 | 375 | 2.3e-159 | 0.9941176470588236 |
| GH2 | 378 | 829 | 3.9e-77 | 0.4867021276595745 |
| CBM57 | 1095 | 1256 | 6e-45 | 0.9863945578231292 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam11721 | Malectin | 2.98e-41 | 1093 | 1269 | 1 | 161 | Di-glucose binding within endoplasmic reticulum. Malectin is a membrane-anchored protein of the endoplasmic reticulum that recognizes and binds Glc2-N-glycan. It carries a signal peptide from residues 1-26, a C-terminal transmembrane helix from residues 255-274, and a highly conserved central part of approximately 190 residues followed by an acidic, glutamate-rich region. Carbohydrate-binding is mediated by the four aromatic residues, Y67, Y89, Y116, and F117 and the aspartate at D186. NMR-based ligand-screening studies has shown binding of the protein to maltose and related oligosaccharides, on the basis of which the protein has been designated "malectin", and its endogenous ligand is found to be Glc2-high-mannose N-glycan. |
| COG3250 | LacZ | 1.30e-34 | 384 | 802 | 10 | 407 | Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism]. |
| PRK10340 | ebgA | 1.60e-25 | 464 | 822 | 117 | 469 | cryptic beta-D-galactosidase subunit alpha; Reviewed |
| PRK10150 | PRK10150 | 3.52e-19 | 473 | 822 | 82 | 442 | beta-D-glucuronidase; Provisional |
| pfam00703 | Glyco_hydro_2 | 1.49e-16 | 567 | 675 | 1 | 106 | Glycosyl hydrolases family 2. This family contains beta-galactosidase, beta-mannosidase and beta-glucuronidase activities. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QMW88020.1 | 0.0 | 1 | 1427 | 1 | 1418 |
| AAO76103.1 | 0.0 | 1 | 1427 | 1 | 1418 |
| QQA06598.1 | 0.0 | 7 | 1427 | 1 | 1413 |
| ALJ42153.1 | 0.0 | 7 | 1427 | 1 | 1413 |
| BCA50092.1 | 0.0 | 7 | 1427 | 1 | 1413 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5MUI_A | 1.47e-276 | 1 | 382 | 1 | 381 | Glycosidehydrolase BT_0996 [Bacteroides thetaiotaomicron VPI-5482] |
| 5MT2_A | 2.12e-267 | 2 | 382 | 2 | 381 | Glycosidehydrolase BT_0996 [Bacteroides thetaiotaomicron VPI-5482],5MUJ_A BT0996 RGII Chain B Complex [Bacteroides thetaiotaomicron VPI-5482] |
| 6D8G_A | 2.28e-53 | 375 | 1261 | 24 | 885 | D341AD367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2 [Bacteroides uniformis str. 3978 T3 ii],6D8G_B D341A D367A calcium binding mutant of Bacteroides uniformis beta-glucuronidase 2 [Bacteroides uniformis str. 3978 T3 ii] |
| 6D50_A | 2.28e-53 | 375 | 1261 | 24 | 885 | Bacteroidesuniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone [Bacteroides uniformis str. 3978 T3 ii],6D50_B Bacteroides uniforms beta-glucuronidase 2 bound to D-glucaro-1,5-lactone [Bacteroides uniformis str. 3978 T3 ii] |
| 5UJ6_A | 8.92e-53 | 379 | 1261 | 20 | 877 | CrystalStructure of Bacteroides Uniformis beta-glucuronidase [Bacteroides uniformis str. 3978 T3 ii],5UJ6_B Crystal Structure of Bacteroides Uniformis beta-glucuronidase [Bacteroides uniformis str. 3978 T3 ii],6NZG_A Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine [Bacteroides uniformis],6NZG_B Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine [Bacteroides uniformis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| T2KPJ7 | 9.14e-48 | 424 | 1066 | 79 | 719 | Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_21970 PE=2 SV=1 |
| T2KM09 | 7.29e-35 | 380 | 1058 | 42 | 700 | Putative beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22050 PE=2 SV=2 |
| T2KN75 | 1.90e-31 | 424 | 1052 | 55 | 670 | Beta-glucuronidase OS=Formosa agariphila (strain DSM 15362 / KCTC 12365 / LMG 23005 / KMM 3901 / M-2Alg 35-1) OX=1347342 GN=BN863_22060 PE=1 SV=1 |
| A7LXS9 | 1.56e-29 | 422 | 801 | 69 | 437 | Beta-galactosidase BoGH2A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02645 PE=1 SV=1 |
| P77989 | 1.06e-25 | 473 | 1019 | 73 | 579 | Beta-galactosidase OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 / 39E) OX=340099 GN=lacZ PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.429439 | 0.538976 | 0.030212 | 0.000504 | 0.000339 | 0.000519 |