You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000000218_01505
You are here: Home > Sequence: MGYG000000218_01505
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Acidaminococcus provencensis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_C; Negativicutes; Acidaminococcales; Acidaminococcaceae; Acidaminococcus; Acidaminococcus provencensis | |||||||||||
| CAZyme ID | MGYG000000218_01505 | |||||||||||
| CAZy Family | GT9 | |||||||||||
| CAZyme Description | Lipopolysaccharide core heptosyltransferase RfaQ | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 28632; End: 29663 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT9 | 75 | 318 | 3.3e-53 | 0.9555555555555556 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd03789 | GT9_LPS_heptosyltransferase | 2.17e-75 | 7 | 336 | 1 | 276 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
| COG0859 | RfaF | 4.82e-63 | 6 | 343 | 2 | 334 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
| pfam01075 | Glyco_transf_9 | 4.28e-35 | 75 | 310 | 2 | 237 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
| TIGR02195 | heptsyl_trn_II | 1.55e-30 | 7 | 339 | 1 | 333 | lipopolysaccharide heptosyltransferase II. This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| PRK10422 | PRK10422 | 5.33e-25 | 1 | 297 | 1 | 303 | lipopolysaccharide core biosynthesis protein; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ADB48007.1 | 5.03e-218 | 2 | 343 | 3 | 344 |
| AEQ22076.1 | 4.93e-190 | 2 | 339 | 3 | 340 |
| QTV78222.1 | 1.51e-169 | 2 | 343 | 6 | 347 |
| QNP77239.1 | 6.95e-162 | 2 | 341 | 3 | 342 |
| BBG62449.1 | 5.68e-161 | 2 | 341 | 3 | 342 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3TOV_A | 1.58e-107 | 2 | 343 | 5 | 349 | Thecrystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008],3TOV_B The crystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008] |
| 1PSW_A | 1.19e-17 | 148 | 336 | 153 | 340 | Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P37421 | 1.49e-20 | 148 | 342 | 153 | 346 | ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1 |
| P25742 | 1.94e-20 | 17 | 295 | 5 | 289 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli (strain K12) OX=83333 GN=rfaQ PE=3 SV=2 |
| P45042 | 2.15e-18 | 17 | 303 | 12 | 308 | ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1 |
| Q9R9D5 | 3.75e-18 | 17 | 295 | 5 | 289 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli OX=562 GN=rfaQ PE=1 SV=1 |
| P37692 | 5.56e-18 | 148 | 336 | 153 | 340 | ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.999990 | 0.000063 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |