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CAZyme Information: MGYG000000235_04227

You are here: Home > Sequence: MGYG000000235_04227

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Enterobacter kobei
Lineage Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Enterobacter; Enterobacter kobei
CAZyme ID MGYG000000235_04227
CAZy Family GH23
CAZyme Description Membrane-bound lytic murein transglycosylase D
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
454 MGYG000000235_23|CGC1 49522.24 10.3513
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000235 4917845 Isolate China Asia
Gene Location Start: 5521;  End: 6885  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000235_04227.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH23 103 247 1.9e-22 0.9333333333333333

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK10783 mltD 0.0 1 454 1 456
membrane-bound lytic murein transglycosylase D; Provisional
cd16894 MltD-like 9.08e-62 111 241 1 129
Membrane-bound lytic murein transglycosylase D and similar proteins. Lytic transglycosylases (LT) catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc). Membrane-bound lytic murein transglycosylase D protein (MltD) family members may have one or more small LysM domains, which may contribute to peptidoglycan binding. Unlike the similar "goose-type" lysozymes, LTs also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as the eukaryotic "goose-type" lysozymes (goose egg-white lysozyme; GEWL).
pfam01464 SLT 1.56e-35 106 219 1 114
Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.
cd00254 LT-like 2.19e-19 126 238 10 108
lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
COG0741 MltE 1.30e-17 2 238 1 278
Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AIX56118.1 0.0 1 454 1 454
QFH89005.1 0.0 1 454 1 454
BBW20553.1 0.0 1 454 1 454
QIP18856.1 0.0 1 454 1 454
QMT05549.1 0.0 1 454 1 454

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1E0G_A 2.29e-23 400 447 1 48
LYSMDomain from E.coli MLTD [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P0AEZ8 2.28e-284 1 454 1 452
Membrane-bound lytic murein transglycosylase D OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) OX=199310 GN=mltD PE=3 SV=1
P0AEZ7 2.28e-284 1 454 1 452
Membrane-bound lytic murein transglycosylase D OS=Escherichia coli (strain K12) OX=83333 GN=mltD PE=1 SV=1
P32820 1.96e-31 92 247 10 168
Putative tributyltin chloride resistance protein OS=Alteromonas sp. (strain M-1) OX=29457 GN=tbtA PE=3 SV=1
P39046 1.14e-10 345 444 565 664
Muramidase-2 OS=Enterococcus hirae (strain ATCC 9790 / DSM 20160 / JCM 8729 / LMG 6399 / NBRC 3181 / NCIMB 6459 / NCDO 1258 / NCTC 12367 / WDCM 00089 / R) OX=768486 GN=EHR_05900 PE=1 SV=1
O34669 2.56e-10 326 451 11 126
Cell wall-binding protein YocH OS=Bacillus subtilis (strain 168) OX=224308 GN=yocH PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as LIPO

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000000 0.000000 1.000048 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000000235_04227.