Species | Varibaculum cambriense_A | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Actinomycetaceae; Varibaculum; Varibaculum cambriense_A | |||||||||||
CAZyme ID | MGYG000000303_01553 | |||||||||||
CAZy Family | GT39 | |||||||||||
CAZyme Description | putative dolichyl-phosphate-mannose--protein mannosyltransferase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 7084; End: 8853 Strand: + |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT39 | 85 | 362 | 1.1e-65 | 0.9865470852017937 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
COG1928 | PMT1 | 6.76e-17 | 79 | 298 | 25 | 223 | Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones]. |
pfam16192 | PMT_4TMC | 2.53e-12 | 397 | 586 | 11 | 198 | C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes. |
pfam02366 | PMT | 3.33e-11 | 147 | 315 | 42 | 213 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
COG1807 | ArnT | 2.35e-08 | 150 | 300 | 64 | 194 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
COG4346 | COG4346 | 1.10e-06 | 150 | 529 | 136 | 429 | Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones]. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
QOX81378.1 | 4.13e-146 | 66 | 589 | 38 | 547 |
QQT14111.1 | 1.07e-127 | 66 | 587 | 11 | 545 |
QQU09498.1 | 1.07e-127 | 66 | 587 | 11 | 545 |
ADI66786.1 | 1.07e-127 | 66 | 587 | 11 | 545 |
QCT34948.1 | 5.16e-120 | 62 | 589 | 57 | 581 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
P9WN04 | 3.55e-72 | 68 | 588 | 34 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2 |
P9WN05 | 3.55e-72 | 68 | 588 | 34 | 521 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2 |
L8F4Z2 | 1.22e-70 | 68 | 588 | 28 | 515 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1 |
Q8NRZ6 | 1.07e-49 | 77 | 588 | 37 | 519 | Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1 |
Q5ADM9 | 1.45e-06 | 66 | 407 | 54 | 356 | Dolichyl-phosphate-mannose--protein mannosyltransferase 2 OS=Candida albicans (strain SC5314 / ATCC MYA-2876) OX=237561 GN=PMT2 PE=1 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
1.000046 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
start | end |
---|---|
170 | 187 |
194 | 216 |
221 | 240 |
334 | 356 |
448 | 467 |
474 | 496 |
500 | 522 |
547 | 569 |
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