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CAZyme Information: MGYG000000486_02056
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Phascolarctobacterium_A sp900770955 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_C; Negativicutes; Acidaminococcales; Acidaminococcaceae; Phascolarctobacterium_A; Phascolarctobacterium_A sp900770955 | |||||||||||
| CAZyme ID | MGYG000000486_02056 | |||||||||||
| CAZy Family | GH23 | |||||||||||
| CAZyme Description | Endo-type membrane-bound lytic murein transglycosylase A | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 11269; End: 11898 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH23 | 69 | 198 | 1.3e-26 | 0.8074074074074075 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd16896 | LT_Slt70-like | 1.43e-76 | 55 | 199 | 2 | 146 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| cd13401 | Slt70-like | 4.29e-52 | 57 | 205 | 6 | 150 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
| cd00254 | LT-like | 3.59e-36 | 72 | 195 | 1 | 108 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| COG0741 | MltE | 4.12e-31 | 56 | 209 | 138 | 292 | Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis]. |
| pfam01464 | SLT | 1.21e-26 | 64 | 171 | 4 | 108 | Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QTV76946.1 | 2.53e-141 | 4 | 209 | 1 | 206 |
| BBG64618.1 | 1.07e-95 | 13 | 209 | 4 | 199 |
| QNP77119.1 | 1.72e-92 | 24 | 209 | 26 | 210 |
| ADB46849.1 | 4.91e-70 | 11 | 209 | 3 | 197 |
| AEQ23289.1 | 2.25e-63 | 11 | 204 | 2 | 193 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5MPQ_A | 3.79e-24 | 53 | 204 | 412 | 559 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
| 5O1J_A | 3.82e-24 | 53 | 204 | 416 | 563 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
| 6FPN_B | 3.86e-24 | 53 | 204 | 422 | 569 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
| 5O24_A | 3.88e-24 | 53 | 204 | 426 | 573 | Lytictransglycosylase in action [Neisseria meningitidis] |
| 5O29_A | 3.91e-24 | 53 | 204 | 432 | 579 | Lytictransglycosylase in action [Neisseria meningitidis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P39434 | 8.70e-16 | 22 | 201 | 454 | 625 | Soluble lytic murein transglycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=slt PE=3 SV=2 |
| P44888 | 3.29e-14 | 77 | 207 | 448 | 578 | Putative soluble lytic murein transglycosylase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=slt PE=3 SV=1 |
| P0AGC4 | 6.20e-14 | 40 | 201 | 467 | 625 | Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1 |
| P0AGC3 | 6.20e-14 | 40 | 201 | 467 | 625 | Soluble lytic murein transglycosylase OS=Escherichia coli (strain K12) OX=83333 GN=slt PE=1 SV=1 |
| O31976 | 8.41e-13 | 53 | 199 | 1418 | 1543 | SPbeta prophage-derived uncharacterized transglycosylase YomI OS=Bacillus subtilis (strain 168) OX=224308 GN=yomI PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.998598 | 0.000674 | 0.000496 | 0.000003 | 0.000002 | 0.000244 |
