DNA-binding transcriptional regulator, LacI/PurR family [Transcription].

Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.

ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. Ligand binding domain of the LacI transcriptional regulator family belonging to the type 1 periplasmic-binding fold protein superfamily. In most cases, ligands are monosaccharide including lactose, ribose, fructose, xylose, arabinose, galactose/glucose, and other sugars. The LacI family of proteins consists of transcriptional regulators related to the lac repressor. In this case, the domain sugar binding changes the DNA binding activity of the repressor domain.

ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria. This group includes the ligand-binding domain of an uncharacterized transcription regulator from Actinobacillus succinogenes and its close homologs from other bacteria. This group belongs to the LacI-GalR family repressors and are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding.

GGDEF domain, diguanylate cyclase (c-di-GMP synthetase) or its enzymatically inactive variants [Signal transduction mechanisms].

ChainA, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXB_B Chain B, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)']

ChainA, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXC_B Chain B, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXC_C Chain C, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXC_D Chain D, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)']

ChainA, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXM_B Chain B, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXM_C Chain C, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXM_D Chain D, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXM_E Chain E, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)'],6ZXM_F Chain F, Putative GGDEF/response regulator receiver domain protein [Leptospira biflexa serovar Patoc strain 'Patoc 1 (Paris)']

ChainA, Diguanylate cyclase [Marinobacter nauticus VT8]

CrystalStructure of GGDEF domain from T.maritima [Thermotoga maritima],4URS_B Crystal Structure of GGDEF domain from T.maritima [Thermotoga maritima]

Diguanylate cyclase VdcA OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) OX=243277 GN=vdcA PE=1 SV=1

Diguanylate cyclase DgcM OS=Escherichia coli O157:H7 OX=83334 GN=dgcM PE=3 SV=2

Diguanylate cyclase DgcM OS=Escherichia coli (strain K12) OX=83333 GN=dgcM PE=1 SV=2

Catabolite control protein A OS=Bacillus subtilis (strain 168) OX=224308 GN=ccpA PE=1 SV=1

HTH-type transcriptional repressor PurR OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) OX=223926 GN=purR PE=3 SV=1