logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000000546_00613

You are here: Home > Sequence: MGYG000000546_00613

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Roseburia sp003483745
Lineage Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Roseburia; Roseburia sp003483745
CAZyme ID MGYG000000546_00613
CAZy Family GH18
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
610 MGYG000000546_15|CGC2 67574.08 4.1615
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000546 3035642 MAG Fiji Oceania
Gene Location Start: 24970;  End: 26802  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000546_00613.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH18 217 595 6.8e-37 0.9222972972972973

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd02874 GH18_CFLE_spore_hydrolase 4.16e-62 265 605 13 313
Cortical fragment-lytic enzyme (CFLE) is a peptidoglycan hydrolase involved in bacterial endospore germination. CFLE is expressed as an inactive preprotein (called SleB) in the forespore compartment of sporulating cells. SleB translocates across the forespore inner membrane and is deposited as a mature enzyme in the cortex layer of the spore. As part of a sensory mechanism capable of initiating germination, CFLE degrades a spore-specific peptidoglycan constituent called muramic-acid delta-lactam that comprises the outer cortex. CFLE has a C-terminal glycosyl hydrolase family 18 (GH18) catalytic domain as well as two N-terminal LysM peptidoglycan-binding domains. In addition to SleB, this family includes YaaH, YdhD, and YvbX from Bacillus subtilis.
COG3858 YaaH 6.93e-41 267 605 116 418
Spore germination protein YaaH [Cell cycle control, cell division, chromosome partitioning].
cd06549 GH18_trifunctional 4.99e-24 252 602 1 298
GH18 domain of an uncharacterized family of bacterial proteins, which share a common three-domain architecture: an N-terminal glycosyl hydrolase family 18 (GH18) domain, a glycosyl transferase family 2 domain, and a C-terminal polysaccharide deacetylase domain.
pfam00704 Glyco_hydro_18 3.15e-21 330 595 81 305
Glycosyl hydrolases family 18.
smart00636 Glyco_18 7.97e-20 329 596 83 333
Glyco_18 domain.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
CBL13521.1 0.0 1 610 1 610
CBL10290.1 0.0 1 610 1 610
VCV23980.1 0.0 1 610 1 610
AEN98276.1 1.79e-296 2 610 5 589
ACR73835.1 2.88e-207 1 610 1 577

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3CZ8_A 1.35e-16 316 596 71 310
ChainA, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168],3CZ8_B Chain B, Putative sporulation-specific glycosylase ydhD [Bacillus subtilis subsp. subtilis str. 168]
4S3J_A 3.68e-15 317 607 172 423
Crystalstructure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_B Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876],4S3J_C Crystal structure of the Bacillus cereus spore cortex-lytic enzyme SleL [Bacillus cereus ATCC 10876]
4S3K_A 6.62e-15 273 605 130 423
ChainA, Spore germination protein YaaH [Priestia megaterium QM B1551]
5JH8_A 5.52e-10 299 607 48 312
Crystalstructure of chitinase from Chromobacterium violaceum ATCC 12472 [Chromobacterium violaceum ATCC 12472]
6JM7_A 1.35e-07 338 467 102 254
Crystalstructure of Ostrinia furnacalis Group IV chitinase [Ostrinia furnacalis],6JMB_A Chain A, ofchtiv-allosamidin [Ostrinia furnacalis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
O32258 1.39e-19 264 607 28 341
Uncharacterized glycosylase YvbX OS=Bacillus subtilis (strain 168) OX=224308 GN=yvbX PE=3 SV=1
O05495 1.41e-16 316 602 163 409
Putative sporulation-specific glycosylase YdhD OS=Bacillus subtilis (strain 168) OX=224308 GN=ydhD PE=1 SV=2
O31682 3.44e-16 268 469 16 214
Putative glycosylase YkvQ OS=Bacillus subtilis (strain 168) OX=224308 GN=ykvQ PE=3 SV=1
P37531 1.13e-14 317 610 169 424
Cortical fragment-lytic enzyme OS=Bacillus subtilis (strain 168) OX=224308 GN=sleL PE=1 SV=2
P0DPJ9 1.10e-13 317 607 171 422
Cortical fragment-lytic enzyme OS=Bacillus anthracis OX=1392 GN=sleL PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.793270 0.143546 0.054157 0.000529 0.000394 0.008114

TMHMM  Annotations      download full data without filtering help

start end
5 27