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CAZyme Information: MGYG000000612_00266

You are here: Home > Sequence: MGYG000000612_00266

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species
Lineage Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Megasphaeraceae; Megasphaera;
CAZyme ID MGYG000000612_00266
CAZy Family GT83
CAZyme Description Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
519 MGYG000000612_11|CGC1 59781.97 9.369
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000612 1970930 MAG Madagascar Africa
Gene Location Start: 15775;  End: 17334  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000000612_00266.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT83 8 422 4e-106 0.8037037037037037

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1807 ArnT 8.48e-57 1 353 1 360
4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis].
PRK13279 arnT 4.27e-37 8 418 5 430
lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase.
pfam13231 PMT_2 7.01e-19 64 215 1 157
Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.
pfam02366 PMT 6.69e-12 39 221 35 236
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.
COG1287 Stt3 1.61e-04 64 315 86 332
Asparagine N-glycosylation enzyme, membrane subunit Stt3 [Posttranslational modification, protein turnover, chaperones].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AVO73979.1 0.0 1 519 1 519
CCC72524.1 0.0 1 519 1 519
AVO26796.1 0.0 1 519 1 519
ALG41392.1 0.0 1 519 1 519
AXL21031.1 6.06e-254 1 519 1 519

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5EZM_A 3.76e-32 11 372 32 412
CrystalStructure of ArnT from Cupriavidus metallidurans in the apo state [Cupriavidus metallidurans CH34],5F15_A Crystal Structure of ArnT from Cupriavidus metallidurans bound to Undecaprenyl phosphate [Cupriavidus metallidurans CH34]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
A6V1N8 1.20e-31 34 324 30 328
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Pseudomonas aeruginosa (strain PA7) OX=381754 GN=arnT PE=3 SV=1
Q02R27 1.20e-31 34 324 30 328
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) OX=208963 GN=arnT PE=3 SV=1
O67270 1.35e-31 14 320 7 314
Uncharacterized protein aq_1220 OS=Aquifex aeolicus (strain VF5) OX=224324 GN=aq_1220 PE=3 SV=1
C5BDQ8 3.08e-31 13 405 9 423
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Edwardsiella ictaluri (strain 93-146) OX=634503 GN=arnT PE=3 SV=1
Q9HY61 4.06e-31 6 324 1 328
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) OX=208964 GN=arnT PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000004 0.000029 0.000001 0.000000 0.000000 0.000001

TMHMM  Annotations      download full data without filtering help

start end
12 31
85 104
116 138
158 189
201 223
251 273
286 303
308 327
340 359
369 389
394 416