Species | Prevotella sp000431975 | |||||||||||
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Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp000431975 | |||||||||||
CAZyme ID | MGYG000000779_01478 | |||||||||||
CAZy Family | GH33 | |||||||||||
CAZyme Description | Sialidase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 6912; End: 8114 Strand: + |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GH33 | 27 | 377 | 1.9e-38 | 0.9181286549707602 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
cd15482 | Sialidase_non-viral | 8.00e-64 | 19 | 387 | 1 | 339 | Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases. |
pfam13088 | BNR_2 | 6.41e-04 | 68 | 149 | 141 | 202 | BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases. |
pfam15902 | Sortilin-Vps10 | 0.001 | 70 | 215 | 6 | 116 | Sortilin, neurotensin receptor 3,. Sortilin, also known in mammals as neurotensin receptor-3, is the archetypical member of a Vps10-domain (Vps10-D) that binds neurotrophic factors and neuropeptides. This domain constitutes the entire luminal part of Sortilin and is activated in the trans-Golgi network by enzymatic propeptide cleavage. The structure of the domain has been determined as a ten-bladed propeller, with up to 9 BNR or beta-hairpin turns in it. The mature receptor binds various ligands, including its own propeptide (Sort-pro), neurotensin, the pro-forms of nerve growth factor-beta (NGF)6 and brain-derived neurotrophic factor (BDNF)7, lipoprotein lipase (LpL), apo lipoprotein AV14 and the receptor-associated protein (RAP)1. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
QYR10380.1 | 5.32e-110 | 1 | 396 | 4 | 395 |
QFQ12979.1 | 3.35e-105 | 10 | 396 | 9 | 397 |
EFC70822.1 | 2.60e-102 | 6 | 396 | 7 | 402 |
ALO48969.1 | 1.29e-101 | 6 | 396 | 11 | 399 |
AWG19756.1 | 6.52e-78 | 17 | 397 | 118 | 499 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
1EUR_A | 1.38e-17 | 26 | 377 | 18 | 348 | Sialidase[Micromonospora viridifaciens],1EUS_A Sialidase Complexed With 2-Deoxy-2,3-Dehydro-N- Acetylneuraminic Acid [Micromonospora viridifaciens] |
1EUT_A | 3.44e-17 | 26 | 377 | 18 | 348 | Sialidase,Large 68kd Form, Complexed With Galactose [Micromonospora viridifaciens],1EUU_A Sialidase Or Neuraminidase, Large 68kd Form [Micromonospora viridifaciens] |
1WCQ_A | 1.09e-16 | 26 | 377 | 14 | 344 | Mutagenesisof the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_B Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_C Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens] |
1W8N_A | 1.94e-16 | 26 | 377 | 14 | 344 | Contributionof the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens. [Micromonospora viridifaciens],1W8O_A Contribution of the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens [Micromonospora viridifaciens] |
2BZD_A | 1.94e-16 | 26 | 377 | 14 | 344 | Galactoserecognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens],2BZD_B Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens],2BZD_C Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
Q02834 | 1.98e-16 | 26 | 377 | 60 | 390 | Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1 |
P31206 | 4.11e-12 | 32 | 243 | 203 | 419 | Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2 |
P10481 | 2.70e-08 | 32 | 239 | 36 | 245 | Sialidase OS=Clostridium perfringens OX=1502 GN=nanH PE=1 SV=1 |
P62575 | 1.81e-06 | 26 | 216 | 333 | 623 | Sialidase A OS=Streptococcus pneumoniae OX=1313 GN=nanA PE=1 SV=1 |
P62576 | 1.81e-06 | 26 | 216 | 333 | 623 | Sialidase A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) OX=171101 GN=nanA PE=1 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
0.000235 | 0.999155 | 0.000163 | 0.000146 | 0.000139 | 0.000133 |
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