You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000000794_01448
You are here: Home > Sequence: MGYG000000794_01448
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Megamonas sp900554895 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_C; Negativicutes; Selenomonadales; Selenomonadaceae; Megamonas; Megamonas sp900554895 | |||||||||||
| CAZyme ID | MGYG000000794_01448 | |||||||||||
| CAZy Family | CBM50 | |||||||||||
| CAZyme Description | Mannosylglucosyl-3-phosphoglycerate phosphatase | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 7838; End: 9451 Strand: + | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| COG0737 | UshA | 9.57e-77 | 8 | 516 | 4 | 498 | 2',3'-cyclic-nucleotide 2'-phosphodiesterase/5'- or 3'-nucleotidase, 5'-nucleotidase family [Nucleotide transport and metabolism, Defense mechanisms]. |
| PRK09558 | ushA | 1.01e-63 | 3 | 523 | 2 | 541 | bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Reviewed |
| PRK09419 | PRK09419 | 2.76e-63 | 31 | 520 | 661 | 1135 | multifunctional 2',3'-cyclic-nucleotide 2'-phosphodiesterase/3'-nucleotidase/5'-nucleotidase. |
| cd00845 | MPP_UshA_N_like | 2.04e-47 | 33 | 285 | 3 | 243 | Escherichia coli UshA-like family, N-terminal metallophosphatase domain. This family includes the bacterial enzyme UshA, and related enzymes including SoxB, CpdB, YhcR, and CD73. All members have a similar domain architecture which includes an N-terminal metallophosphatase domain and a C-terminal nucleotidase domain. The N-terminal metallophosphatase domain belongs to a large superfamily of distantly related metallophosphatases (MPPs) that includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination. |
| pfam02872 | 5_nucleotid_C | 2.66e-42 | 320 | 493 | 2 | 154 | 5'-nucleotidase, C-terminal domain. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ADL06114.1 | 1.14e-205 | 3 | 537 | 7 | 609 |
| QRV19771.1 | 1.14e-205 | 3 | 537 | 7 | 609 |
| SET94084.1 | 6.06e-203 | 25 | 537 | 31 | 609 |
| QJU22404.1 | 9.46e-201 | 21 | 537 | 32 | 614 |
| ASN98642.1 | 5.41e-200 | 21 | 537 | 32 | 614 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 2Z1A_A | 5.63e-42 | 69 | 514 | 79 | 515 | Crystalstructure of 5'-nucleotidase precursor from Thermus thermophilus HB8 [Thermus thermophilus HB8] |
| 7JV8_A | 2.20e-36 | 25 | 513 | 1 | 510 | HumanCD73 (ecto 5'-nucleotidase) in complex with compound 35 [Homo sapiens],7JV8_B Human CD73 (ecto 5'-nucleotidase) in complex with compound 35 [Homo sapiens],7JV8_C Human CD73 (ecto 5'-nucleotidase) in complex with compound 35 [Homo sapiens],7JV8_D Human CD73 (ecto 5'-nucleotidase) in complex with compound 35 [Homo sapiens] |
| 6XUQ_A | 3.01e-36 | 19 | 513 | 10 | 525 | HumanEcto-5'-nucleotidase (CD73) in complex with A1618 (compound 1b in publication) in the closed state in crystal form III [Homo sapiens],6Z9D_A Human Ecto-5'-nucleotidase (CD73) in complex with AOPCP derivative AB680 (compound 55 in publication) in the closed form (crystal form III) [Homo sapiens] |
| 4H2F_A | 3.64e-36 | 33 | 513 | 28 | 529 | Humanecto-5'-nucleotidase (CD73): crystal form I (open) in complex with adenosine [Homo sapiens],4H2G_A Human ecto-5'-nucleotidase (CD73): crystal form II (open) in complex with adenosine [Homo sapiens] |
| 7QGA_A | 3.68e-36 | 33 | 513 | 5 | 506 | ChainA, 5'-nucleotidase [Homo sapiens],7QGL_A Chain A, 5'-nucleotidase [Homo sapiens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A9BJC1 | 4.25e-52 | 3 | 520 | 2 | 487 | Mannosylglucosyl-3-phosphoglycerate phosphatase OS=Petrotoga mobilis (strain DSM 10674 / SJ95) OX=403833 GN=mggB PE=1 SV=1 |
| Q05927 | 1.16e-38 | 20 | 513 | 16 | 532 | 5'-nucleotidase OS=Bos taurus OX=9913 GN=NT5E PE=1 SV=2 |
| O34313 | 2.36e-36 | 33 | 534 | 671 | 1174 | Trifunctional nucleotide phosphoesterase protein YfkN OS=Bacillus subtilis (strain 168) OX=224308 GN=yfkN PE=1 SV=1 |
| B6EWW8 | 4.81e-36 | 23 | 514 | 36 | 548 | Snake venom 5'-nucleotidase OS=Gloydius brevicaudus OX=259325 PE=2 SV=1 |
| P22848 | 4.94e-36 | 33 | 523 | 40 | 543 | 5'-nucleotidase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) OX=223926 GN=nutA PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000343 | 0.998855 | 0.000211 | 0.000200 | 0.000194 | 0.000171 |
