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CAZyme Information: MGYG000000959_00923

You are here: Home > Sequence: MGYG000000959_00923

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Ruminococcus sp900752785
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminococcus; Ruminococcus sp900752785
CAZyme ID MGYG000000959_00923
CAZy Family GH48
CAZyme Description Cellulose 1,4-beta-cellobiosidase (reducing end) CelS
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
841 MGYG000000959_17|CGC1 92039.55 4.2628
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000000959 2365658 MAG Denmark Europe
Gene Location Start: 28195;  End: 30720  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 3.2.1.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH48 46 745 2.9e-203 0.9934533551554828

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam02011 Glyco_hydro_48 0.0 46 749 1 620
Glycosyl hydrolase family 48. Members of this family are endoglucanase EC:3.2.1.4 and exoglucanase EC:3.2.1.91 enzymes that cleave cellulose or related substrate.
cd14256 Dockerin_I 3.05e-07 773 831 2 57
Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.
pfam00404 Dockerin_1 0.006 773 817 1 41
Dockerin type I repeat. The dockerin repeat is the binding partner of the cohesin domain pfam00963. The cohesin-dockerin interaction is the crucial interaction for complex formation in the cellulosome. The dockerin repeats, each bearing homology to the EF-hand calcium-binding loop bind calcium.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ADX05724.1 0.0 1 796 1 806
CBL17316.1 6.09e-284 1 834 1 797
CAS03459.1 1.26e-241 1 751 1 778
AAR01217.1 1.61e-240 7 765 2 786
ADU23081.1 2.28e-240 1 752 1 779

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5YJ6_A 5.70e-155 45 751 12 636
ChainA, Dockerin type I repeat-containing protein [Acetivibrio thermocellus DSM 1313]
1L1Y_A 4.56e-154 45 752 39 664
ChainA, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_B Chain B, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_C Chain C, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_D Chain D, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_E Chain E, cellobiohydrolase [Acetivibrio thermocellus],1L1Y_F Chain F, cellobiohydrolase [Acetivibrio thermocellus],1L2A_A Chain A, cellobiohydrolase [Acetivibrio thermocellus],1L2A_B Chain B, cellobiohydrolase [Acetivibrio thermocellus],1L2A_C Chain C, cellobiohydrolase [Acetivibrio thermocellus],1L2A_D Chain D, cellobiohydrolase [Acetivibrio thermocellus],1L2A_E Chain E, cellobiohydrolase [Acetivibrio thermocellus],1L2A_F Chain F, cellobiohydrolase [Acetivibrio thermocellus]
4XWL_A 1.10e-152 43 754 45 676
Catalyticdomain of Clostridium Cellulovorans Exgs [Clostridium cellulovorans],4XWM_A Complex structure of catalytic domain of Clostridium Cellulovorans Exgs and Cellobiose [Clostridium cellulovorans],4XWN_A Complex structure of catalytic domain of Clostridium Cellulovorans Exgs and Cellotetraose [Clostridium cellulovorans]
6D5D_A 2.84e-152 39 749 14 642
Structureof Caldicellulosiruptor danielii GH48 module of glycoside hydrolase WP_045175321 [Caldicellulosiruptor danielii]
1F9O_A 5.11e-148 42 751 5 629
Crystalstructure of the cellulase Cel48F from C. Cellulolyticum with the thiooligosaccharide inhibitor PIPS-IG3 [Ruminiclostridium cellulolyticum],1FAE_A Crystal structure of the cellulase CEL48F from C. cellulolyticum in complex with cellobiose [Ruminiclostridium cellulolyticum],1FBO_A Crystal structure of the cellulase CEL48F from C. cellulolyticum in complex with cellobiitol [Ruminiclostridium cellulolyticum],1FCE_A PROCESSIVE ENDOCELLULASE CELF OF CLOSTRIDIUM CELLULOLYTICUM [Ruminiclostridium cellulolyticum],1G9G_A Xtal-Structure Of The Free Native Cellulase Cel48f [Ruminiclostridium cellulolyticum]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
A3DH67 5.15e-158 45 789 39 694
Cellulose 1,4-beta-cellobiosidase (reducing end) CelS OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=celS PE=1 SV=1
P0C2S5 5.15e-158 45 789 39 694
Cellulose 1,4-beta-cellobiosidase (reducing end) CelS OS=Acetivibrio thermocellus OX=1515 GN=celS PE=1 SV=1
P50900 1.59e-149 44 749 42 655
Exoglucanase-2 OS=Thermoclostridium stercorarium (strain ATCC 35414 / DSM 8532 / NCIMB 11754) OX=1121335 GN=celY PE=1 SV=2
P37698 2.48e-149 20 795 12 688
Endoglucanase F OS=Ruminiclostridium cellulolyticum (strain ATCC 35319 / DSM 5812 / JCM 6584 / H10) OX=394503 GN=celCCF PE=1 SV=2
P22534 1.78e-138 78 737 1140 1727
Endoglucanase A OS=Caldicellulosiruptor saccharolyticus OX=44001 GN=celA PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000239 0.999090 0.000153 0.000192 0.000155 0.000128

TMHMM  Annotations      download full data without filtering help

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