beta-diglucosyldiacylglycerol synthase and similar proteins. beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.

Diacylglycerol kinase family enzyme [Lipid transport and metabolism, General function prediction only].

putative lipid kinase; Reviewed

putative lipid kinase; Reviewed

lipid kinase, YegS/Rv2252/BmrU family. The E. coli member of this family, YegS has been purified and shown to have phosphatidylglycerol kinase activity. The member from M. tuberculosis, Rv2252, has diacylglycerol kinase activity. BmrU from B. subtilis is in an operon with multidrug efflux transporter Bmr, but is uncharacterized. [Unknown function, Enzymes of unknown specificity]

CrystalStructure of Diacylglycerol Kinase DgkB in complex with ADP and Mg [Staphylococcus aureus],2QVL_A Crystal Structure of Diacylglycerol Kinase [Staphylococcus aureus]

ChainA, putative diacylglycerol kinase [Bacillus anthracis str. Sterne],4WRR_B Chain B, putative diacylglycerol kinase [Bacillus anthracis str. Sterne],4WRR_C Chain C, putative diacylglycerol kinase [Bacillus anthracis str. Sterne],4WRR_D Chain D, putative diacylglycerol kinase [Bacillus anthracis str. Sterne]

Thecrystal structure of a diacylglycerol kinases from Bacillus anthracis str. Sterne [Bacillus anthracis str. Sterne],3S40_B The crystal structure of a diacylglycerol kinases from Bacillus anthracis str. Sterne [Bacillus anthracis str. Sterne],3S40_C The crystal structure of a diacylglycerol kinases from Bacillus anthracis str. Sterne [Bacillus anthracis str. Sterne],3S40_D The crystal structure of a diacylglycerol kinases from Bacillus anthracis str. Sterne [Bacillus anthracis str. Sterne]

ChainA, BmrU protein [Bacillus anthracis str. Sterne],3T5P_B Chain B, BmrU protein [Bacillus anthracis str. Sterne],3T5P_C Chain C, BmrU protein [Bacillus anthracis str. Sterne],3T5P_D Chain D, BmrU protein [Bacillus anthracis str. Sterne],3T5P_E Chain E, BmrU protein [Bacillus anthracis str. Sterne],3T5P_F Chain F, BmrU protein [Bacillus anthracis str. Sterne],3T5P_G Chain G, BmrU protein [Bacillus anthracis str. Sterne],3T5P_H Chain H, BmrU protein [Bacillus anthracis str. Sterne],3T5P_I Chain I, BmrU protein [Bacillus anthracis str. Sterne],3T5P_J Chain J, BmrU protein [Bacillus anthracis str. Sterne],3T5P_K Chain K, BmrU protein [Bacillus anthracis str. Sterne],3T5P_L Chain L, BmrU protein [Bacillus anthracis str. Sterne]

Thecrystal structure of Arabidopsis thaliana galactolipid synthase, MGD1 (apo-form) [Arabidopsis thaliana],4X1T_A The crystal structure of Arabidopsis thaliana galactolipid synthase MGD1 in complex with UDP [Arabidopsis thaliana]

Diacylglycerol kinase OS=Bacillus subtilis (strain 168) OX=224308 GN=dagK PE=1 SV=1

Diacylglycerol kinase OS=Staphylococcus aureus (strain bovine RF122 / ET3-1) OX=273036 GN=dagK PE=3 SV=1

Diacylglycerol kinase OS=Staphylococcus aureus (strain MRSA252) OX=282458 GN=dagK PE=1 SV=1

Diacylglycerol kinase OS=Staphylococcus aureus (strain USA300) OX=367830 GN=dagK PE=3 SV=1

Diacylglycerol kinase OS=Staphylococcus aureus (strain MSSA476) OX=282459 GN=dagK PE=3 SV=1