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CAZyme Information: MGYG000001261_01432
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Caulobacter sp903900155 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales; Caulobacteraceae; Caulobacter; Caulobacter sp903900155 | |||||||||||
| CAZyme ID | MGYG000001261_01432 | |||||||||||
| CAZy Family | GH23 | |||||||||||
| CAZyme Description | Membrane-bound lytic murein transglycosylase C | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 5594; End: 7249 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH23 | 375 | 503 | 1.1e-24 | 0.7851851851851852 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd13401 | Slt70-like | 3.72e-47 | 359 | 507 | 2 | 152 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
| cd00254 | LT-like | 4.06e-34 | 375 | 502 | 2 | 111 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| cd16896 | LT_Slt70-like | 8.98e-34 | 372 | 501 | 17 | 144 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| COG0741 | MltE | 1.20e-28 | 370 | 517 | 150 | 296 | Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis]. |
| cd16893 | LT_MltC_MltE | 1.78e-26 | 370 | 501 | 10 | 161 | membrane-bound lytic murein transglycosylases MltC and MltE, and similar proteins. MltC and MltE are periplasmic, outer membrane attached lytic transglycosylases (LTs), which cleave beta-1,4-glycosidic bonds joining N-acetylmuramic acid and N-acetylglucosamine in the cell wall peptidoglycan, yielding 1,6-anhydromuropeptides. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AZS23453.1 | 1.34e-306 | 8 | 546 | 2 | 540 |
| ATC28146.1 | 3.46e-302 | 8 | 546 | 2 | 540 |
| AAK23313.1 | 3.46e-302 | 8 | 546 | 2 | 540 |
| ATC24265.1 | 3.46e-302 | 8 | 546 | 2 | 540 |
| AZH12511.1 | 3.46e-302 | 8 | 546 | 2 | 540 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5O1J_A | 1.02e-18 | 205 | 510 | 273 | 565 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
| 5MPQ_A | 1.77e-18 | 205 | 510 | 269 | 561 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
| 6FPN_B | 1.82e-18 | 205 | 510 | 279 | 571 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
| 5O24_A | 1.84e-18 | 205 | 510 | 283 | 575 | Lytictransglycosylase in action [Neisseria meningitidis] |
| 5O29_A | 1.86e-18 | 205 | 510 | 289 | 581 | Lytictransglycosylase in action [Neisseria meningitidis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P0AGC3 | 2.50e-16 | 189 | 523 | 326 | 644 | Soluble lytic murein transglycosylase OS=Escherichia coli (strain K12) OX=83333 GN=slt PE=1 SV=1 |
| P0AGC4 | 2.50e-16 | 189 | 523 | 326 | 644 | Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1 |
| P39434 | 1.02e-15 | 185 | 509 | 322 | 630 | Soluble lytic murein transglycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=slt PE=3 SV=2 |
| O31608 | 1.03e-14 | 370 | 502 | 71 | 180 | Putative murein lytic transglycosylase YjbJ OS=Bacillus subtilis (strain 168) OX=224308 GN=yjbJ PE=3 SV=1 |
| P44888 | 4.21e-12 | 372 | 512 | 441 | 580 | Putative soluble lytic murein transglycosylase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=slt PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.036174 | 0.934922 | 0.027961 | 0.000315 | 0.000303 | 0.000321 |