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CAZyme Information: MGYG000001330_01125
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Helicobacter_D winghamensis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Campylobacterota; Campylobacteria; Campylobacterales; Helicobacteraceae; Helicobacter_D; Helicobacter_D winghamensis | |||||||||||
| CAZyme ID | MGYG000001330_01125 | |||||||||||
| CAZy Family | GT19 | |||||||||||
| CAZyme Description | Lipid-A-disaccharide synthase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 104781; End: 105959 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT19 | 6 | 356 | 2.5e-76 | 0.9350282485875706 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK14089 | PRK14089 | 3.96e-142 | 5 | 386 | 3 | 347 | lipid-A-disaccharide synthase. |
| COG0763 | LpxB | 3.45e-78 | 3 | 376 | 1 | 367 | Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis]. |
| TIGR00215 | lpxB | 2.96e-70 | 6 | 384 | 8 | 384 | lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| pfam02684 | LpxB | 2.31e-68 | 6 | 376 | 1 | 370 | Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide. |
| PRK00025 | lpxB | 1.52e-51 | 70 | 351 | 57 | 334 | lipid-A-disaccharide synthase; Reviewed |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QOQ98371.1 | 7.29e-288 | 1 | 392 | 1 | 392 |
| VEJ06254.1 | 4.15e-158 | 2 | 392 | 3 | 376 |
| AWI33989.1 | 1.23e-147 | 1 | 392 | 3 | 377 |
| BAF70422.1 | 3.04e-89 | 4 | 380 | 1 | 341 |
| AYJ79263.1 | 9.72e-88 | 4 | 389 | 1 | 347 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5W8S_A | 2.43e-18 | 98 | 313 | 92 | 317 | LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)] |
| 5W8N_A | 4.43e-18 | 98 | 313 | 92 | 317 | LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q17WJ2 | 1.31e-86 | 6 | 387 | 4 | 357 | Lipid-A-disaccharide synthase OS=Helicobacter acinonychis (strain Sheeba) OX=382638 GN=lpxB PE=3 SV=1 |
| Q9ZKY2 | 1.85e-86 | 6 | 387 | 4 | 357 | Lipid-A-disaccharide synthase OS=Helicobacter pylori (strain J99 / ATCC 700824) OX=85963 GN=lpxB PE=3 SV=1 |
| B5Z7M7 | 3.69e-86 | 6 | 387 | 4 | 357 | Lipid-A-disaccharide synthase OS=Helicobacter pylori (strain G27) OX=563041 GN=lpxB PE=3 SV=1 |
| O25537 | 8.30e-85 | 6 | 387 | 4 | 357 | Lipid-A-disaccharide synthase OS=Helicobacter pylori (strain ATCC 700392 / 26695) OX=85962 GN=lpxB PE=3 SV=1 |
| Q1CT05 | 4.67e-84 | 6 | 387 | 4 | 357 | Lipid-A-disaccharide synthase OS=Helicobacter pylori (strain HPAG1) OX=357544 GN=lpxB PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000043 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |