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CAZyme Information: MGYG000001419_02430
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Timonella senegalensis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Cellulomonadaceae; Timonella; Timonella senegalensis | |||||||||||
| CAZyme ID | MGYG000001419_02430 | |||||||||||
| CAZy Family | GH23 | |||||||||||
| CAZyme Description | Resuscitation-promoting factor Rpf2 | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 226318; End: 227580 Strand: + | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd13925 | RPF | 4.80e-32 | 346 | 413 | 3 | 71 | core lysozyme-like domain of resuscitation-promoting factor proteins. Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF. |
| COG3583 | YabE | 1.09e-28 | 3 | 363 | 13 | 309 | Uncharacterized conserved protein YabE, contains G5 and tandem DUF348 domains [Function unknown]. |
| pfam06737 | Transglycosylas | 1.36e-26 | 342 | 413 | 1 | 75 | Transglycosylase-like domain. This family of proteins are very likely to act as transglycosylase enzymes related to pfam00062 and pfam01464. These other families are weakly matched by this family, and include the known active site residues. |
| pfam07501 | G5 | 8.63e-11 | 233 | 308 | 1 | 75 | G5 domain. This domain is found in a wide range of extracellular proteins. It is found tandemly repeated in up to 8 copies. It is found in the N-terminus of peptidases belonging to the M26 family which cleave human IgA. The domain is also found in proteins involved in metabolism of bacterial cell walls suggesting this domain may have an adhesive function. |
| pfam03990 | DUF348 | 1.13e-09 | 30 | 68 | 1 | 39 | Domain of unknown function (DUF348). This domain normally occurs as tandem repeats; however it is found as a single copy in the S. cerevisiae DNA-binding nuclear protein YCR593. This protein is involved in sporulation part of the SET3C complex, which is required to repress early/middle sporulation genes during meiosis. The bacterial proteins are likely to be involved in a cell wall function as they are found in conjunction with the pfam07501 domain, which is involved in various cell surface processes. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| ACV09592.1 | 2.57e-134 | 1 | 419 | 16 | 438 |
| SQH22044.1 | 2.57e-134 | 1 | 419 | 16 | 438 |
| AVJ53347.1 | 9.14e-131 | 23 | 419 | 2 | 401 |
| SDS22219.1 | 1.28e-109 | 9 | 420 | 47 | 435 |
| ANC32685.1 | 1.09e-100 | 2 | 420 | 46 | 439 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4CGE_A | 4.99e-18 | 346 | 416 | 4 | 74 | ChainA, Resuscitation-promoting Factor Rpfe [Mycobacterium tuberculosis],4CGE_B Chain B, Resuscitation-promoting Factor Rpfe [Mycobacterium tuberculosis],4CGE_C Chain C, Resuscitation-promoting Factor Rpfe [Mycobacterium tuberculosis],4CGE_D Chain D, Resuscitation-promoting Factor Rpfe [Mycobacterium tuberculosis],4CGE_E Chain E, Resuscitation-promoting Factor Rpfe [Mycobacterium tuberculosis],4CGE_F Chain F, Resuscitation-promoting Factor Rpfe [Mycobacterium tuberculosis] |
| 2N5Z_A | 2.69e-16 | 338 | 419 | 1 | 82 | Mycobacteriumtuberculosis: a dynamic view of the resuscitation promoting factor RpfC catalytic domain [Mycobacterium tuberculosis H37Rv] |
| 4OW1_A | 9.06e-16 | 346 | 419 | 6 | 79 | ChainA, Resuscitation-promoting factor RpfC [Mycobacterium tuberculosis],4OW1_B Chain B, Resuscitation-promoting factor RpfC [Mycobacterium tuberculosis],4OW1_E Chain E, Resuscitation-promoting factor RpfC [Mycobacterium tuberculosis],4OW1_S Chain S, Resuscitation-promoting factor RpfC [Mycobacterium tuberculosis],4OW1_T Chain T, Resuscitation-promoting factor RpfC [Mycobacterium tuberculosis],4OW1_U Chain U, Resuscitation-promoting factor RpfC [Mycobacterium tuberculosis],4OW1_W Chain W, Resuscitation-promoting factor RpfC [Mycobacterium tuberculosis],4OW1_X Chain X, Resuscitation-promoting factor RpfC [Mycobacterium tuberculosis] |
| 1XSF_A | 1.90e-15 | 332 | 418 | 16 | 106 | ChainA, Probable resuscitation-promoting factor rpfB [Mycobacterium tuberculosis] |
| 4KL7_A | 2.32e-15 | 345 | 418 | 2 | 78 | ChainA, Resuscitation-promoting factor RpfB [Mycobacterium tuberculosis],4KL7_B Chain B, Resuscitation-promoting factor RpfB [Mycobacterium tuberculosis],4KL7_C Chain C, Resuscitation-promoting factor RpfB [Mycobacterium tuberculosis],4KL7_D Chain D, Resuscitation-promoting factor RpfB [Mycobacterium tuberculosis],4KPM_A Chain A, Resuscitation-promoting factor RpfB [Mycobacterium tuberculosis],4KPM_B Chain B, Resuscitation-promoting factor RpfB [Mycobacterium tuberculosis],4KPM_C Chain C, Resuscitation-promoting factor RpfB [Mycobacterium tuberculosis],4KPM_D Chain D, Resuscitation-promoting factor RpfB [Mycobacterium tuberculosis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q6M6N7 | 7.44e-35 | 4 | 419 | 19 | 373 | Resuscitation-promoting factor Rpf2 OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=rpf2 PE=1 SV=1 |
| A0R3E0 | 1.13e-21 | 20 | 418 | 16 | 360 | Resuscitation-promoting factor RpfB OS=Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) OX=246196 GN=rpfB PE=3 SV=2 |
| O86308 | 1.11e-19 | 345 | 419 | 46 | 120 | Resuscitation-promoting factor Rpf OS=Micrococcus luteus OX=1270 GN=rpf PE=1 SV=2 |
| P9WG28 | 7.86e-18 | 7 | 418 | 4 | 360 | Resuscitation-promoting factor RpfB OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=rpfB PE=3 SV=1 |
| P9WG29 | 7.86e-18 | 7 | 418 | 4 | 360 | Resuscitation-promoting factor RpfB OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=rpfB PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.670981 | 0.309696 | 0.017645 | 0.000799 | 0.000342 | 0.000528 |
