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CAZyme Information: MGYG000001443_05555

You are here: Home > Sequence: MGYG000001443_05555

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Streptomyces albus
Lineage Bacteria; Actinobacteriota; Actinomycetia; Streptomycetales; Streptomycetaceae; Streptomyces; Streptomyces albus
CAZyme ID MGYG000001443_05555
CAZy Family GT20
CAZyme Description Trehalose-6-phosphate synthase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
480 MGYG000001443_6|CGC3 52718.25 5.5835
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001443 7820353 Isolate not provided not provided
Gene Location Start: 738194;  End: 739636  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.15

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT20 1 478 2.8e-146 0.9642105263157895

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd03788 GT20_TPS 1.27e-139 2 478 3 462
trehalose-6-phosphate synthase. Trehalose-6-Phosphate Synthase (TPS, EC 2.4.1.15) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain.
pfam00982 Glyco_transf_20 1.02e-127 2 478 4 468
Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex,.
COG0380 OtsA 2.12e-121 3 478 19 477
Trehalose-6-phosphate synthase [Carbohydrate transport and metabolism].
PRK14501 PRK14501 2.40e-105 2 479 4 461
putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional
PLN03063 PLN03063 9.26e-68 83 478 89 475
alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QID36950.1 0.0 1 480 19 498
QNF56593.1 2.00e-261 1 479 14 500
QHF92828.1 2.00e-261 1 479 14 500
QEV76339.1 2.56e-258 1 478 10 484
QDA05060.1 2.56e-258 1 478 10 484

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5LQD_A 1.37e-182 1 478 17 462
Trehalose-6-phosphatesynthase, GDP-glucose-dependent OtsA [Streptomyces venezuelae ATCC 10712],5LQD_B Trehalose-6-phosphate synthase, GDP-glucose-dependent OtsA [Streptomyces venezuelae ATCC 10712],5LQD_C Trehalose-6-phosphate synthase, GDP-glucose-dependent OtsA [Streptomyces venezuelae ATCC 10712],5LQD_D Trehalose-6-phosphate synthase, GDP-glucose-dependent OtsA [Streptomyces venezuelae ATCC 10712]
6JBI_A 2.84e-62 1 458 2 442
Structureof Tps1 apo structure [Pyricularia oryzae 70-15],6JBI_B Structure of Tps1 apo structure [Pyricularia oryzae 70-15],6JBR_A Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_B Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_D Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_F Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_H Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_K Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_M Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBR_O Tps1/UDP/T6P complex [Pyricularia oryzae 70-15],6JBW_A Structure of Tps1/UDP complex [Pyricularia oryzae 70-15],6JBW_B Structure of Tps1/UDP complex [Pyricularia oryzae 70-15]
5HVO_A 5.77e-61 1 470 13 466
Structureof Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_B Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_C Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVO_D Structure of Aspergillus fumigatus trehalose-6-phosphate synthase B in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293]
5JIJ_A 1.35e-60 2 480 14 476
ChainA, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5JIO_A Chain A, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5K41_A Chain A, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5K42_A Chain A, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5K44_A Chain A, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5K5C_A Chain A, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5L3K_A Chain A, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5L3K_B Chain B, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5L3K_C Chain C, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5L3K_D Chain D, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5L3K_E Chain E, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5L3K_F Chain F, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5L3K_G Chain G, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile],5L3K_H Chain H, Alpha,alpha-trehalose-phosphate synthase [Mycolicibacterium thermoresistibile]
5HVM_A 1.32e-59 1 451 14 447
Structureof Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293],5HVM_B Structure of Aspergillus fumigatus trehalose-6-phosphate synthase A in complex with UDP and validoxylamine A [Aspergillus fumigatus Af293]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
G4RK44 1.22e-64 1 478 3 463
Bifunctional trehalose-6-phosphate synthase/phosphatase OS=Thermoproteus tenax (strain ATCC 35583 / DSM 2078 / JCM 9277 / NBRC 100435 / Kra 1) OX=768679 GN=tpsp PE=1 SV=1
P40387 5.97e-63 1 458 21 461
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) OX=284812 GN=tps1 PE=1 SV=2
Q743L8 4.07e-61 2 478 20 484
Trehalose-6-phosphate synthase OS=Mycolicibacterium paratuberculosis (strain ATCC BAA-968 / K-10) OX=262316 GN=otsA PE=3 SV=1
A0QAK7 5.68e-61 2 478 20 484
Trehalose-6-phosphate synthase OS=Mycobacterium avium (strain 104) OX=243243 GN=otsA PE=3 SV=1
A1UM30 2.84e-60 2 478 17 477
Trehalose-6-phosphate synthase OS=Mycobacterium sp. (strain KMS) OX=189918 GN=otsA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000043 0.000018 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001443_05555.