logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000001491_00639

You are here: Home > Sequence: MGYG000001491_00639

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Rubeoparvulum massiliense
Lineage Bacteria; Firmicutes; Bacilli; Rubeoparvulales; Rubeoparvulaceae; Rubeoparvulum; Rubeoparvulum massiliense
CAZyme ID MGYG000001491_00639
CAZy Family GT1
CAZyme Description Demethyllactenocin mycarosyltransferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
393 44298.8 6.3083
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001491 2843796 Isolate not provided not provided
Gene Location Start: 106985;  End: 108166  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001491_00639.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT1 197 388 2.6e-37 0.468586387434555

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
TIGR01426 MGT 3.21e-103 7 388 1 389
glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]
COG1819 YjiC 2.77e-73 1 389 1 399
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism].
cd03784 GT1_Gtf-like 4.61e-69 3 388 2 404
UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.
cd03785 GT28_MurG 2.05e-12 13 388 11 350
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
pfam00201 UDPGT 1.02e-07 269 373 299 423
UDP-glucoronosyl and UDP-glucosyl transferase.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
BAK99922.1 8.66e-199 1 389 1 389
QNB67245.1 2.54e-149 1 390 1 388
ANP68408.1 2.54e-149 1 390 1 388
AND83635.1 2.54e-149 1 390 1 388
AXU51328.1 4.15e-148 1 389 1 387

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
6KQW_A 2.93e-59 4 391 6 387
ChainA, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168]
6KQX_A 3.32e-59 4 391 6 387
ChainA, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168],7BOV_A Chain A, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168]
2IYA_A 1.07e-41 4 389 15 420
Thecrystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering [Streptomyces antibioticus],2IYA_B The crystal structure of macrolide glycosyltransferases: A blueprint for antibiotic engineering [Streptomyces antibioticus]
3IA7_A 9.39e-35 4 391 7 399
CrystalStructure of CalG4, the Calicheamicin Glycosyltransferase [Micromonospora echinospora],3IA7_B Crystal Structure of CalG4, the Calicheamicin Glycosyltransferase [Micromonospora echinospora]
3RSC_A 4.25e-34 2 389 21 412
CrystalStructure of CalG2, Calicheamicin Glycosyltransferase, TDP and calicheamicin T0 bound form [Micromonospora echinospora],3RSC_B Crystal Structure of CalG2, Calicheamicin Glycosyltransferase, TDP and calicheamicin T0 bound form [Micromonospora echinospora]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
O31853 3.65e-62 1 392 1 399
Uncharacterized UDP-glucosyltransferase YojK OS=Bacillus subtilis (strain 168) OX=224308 GN=yojK PE=3 SV=2
O34539 1.82e-58 4 391 6 387
NDP-glycosyltransferase YjiC OS=Bacillus subtilis (strain 168) OX=224308 GN=yjiC PE=1 SV=1
O05496 5.44e-58 1 392 1 393
Uncharacterized UDP-glucosyltransferase YdhE OS=Bacillus subtilis (strain 168) OX=224308 GN=ydhE PE=3 SV=2
Q65JC2 1.10e-57 4 389 6 390
NDP-glycosyltransferase YjiC OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) OX=279010 GN=yjiC PE=1 SV=1
Q9XC67 1.56e-40 1 390 58 458
Demethyllactenocin mycarosyltransferase OS=Streptomyces fradiae OX=1906 GN=tylCV PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000063 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000001491_00639.