You are browsing environment: HUMAN GUT
CAZyme Information: MGYG000001535_00990
You are here: Home > Sequence: MGYG000001535_00990
Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Paenibacillus_A phocaensis | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes; Bacilli; Paenibacillales; Paenibacillaceae; Paenibacillus_A; Paenibacillus_A phocaensis | |||||||||||
| CAZyme ID | MGYG000001535_00990 | |||||||||||
| CAZy Family | PL8 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
|
|||||||||||
| Genome Property |
|
|||||||||||
| Gene Location | Start: 389674; End: 396096 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| PL8 | 984 | 1216 | 1.5e-59 | 0.9536679536679536 |
| CBM32 | 1476 | 1590 | 7.7e-30 | 0.9274193548387096 |
| CBM32 | 1347 | 1460 | 1.8e-24 | 0.9274193548387096 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd01083 | GAG_Lyase | 2.12e-119 | 651 | 1291 | 4 | 693 | Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase. |
| pfam02278 | Lyase_8 | 3.14e-70 | 986 | 1216 | 12 | 252 | Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. |
| pfam00754 | F5_F8_type_C | 2.11e-23 | 1474 | 1588 | 1 | 125 | F5/8 type C domain. This domain is also known as the discoidin (DS) domain family. |
| pfam00754 | F5_F8_type_C | 9.76e-20 | 1346 | 1458 | 2 | 125 | F5/8 type C domain. This domain is also known as the discoidin (DS) domain family. |
| NF033190 | inl_like_NEAT_1 | 8.88e-19 | 1953 | 2140 | 569 | 754 | NEAT domain-containing leucine-rich repeat protein. Members of this family have an N-terminal NEAT (near transporter) domain often associated with iron transport, followed by a leucine-rich repeat region with significant sequence similarity to the internalins of Listeria monocytogenes. However, since Bacillus cereus (from which this protein was described, in PMID:16978259) is not considered an intracellular pathogen, and the function may be iron transport rather than internalization, applying the name "internalin" to this family probably would be misleading. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QMV41393.1 | 0.0 | 1 | 2139 | 1 | 2235 |
| CQR51520.1 | 0.0 | 640 | 2139 | 39 | 1610 |
| QQZ62770.1 | 0.0 | 649 | 2139 | 1 | 1563 |
| QUL55219.1 | 0.0 | 637 | 2139 | 12 | 1488 |
| AZM50462.1 | 3.55e-256 | 640 | 1592 | 34 | 972 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1CB8_A | 5.70e-67 | 686 | 1291 | 32 | 639 | CHONDROITINASEAC LYASE FROM FLAVOBACTERIUM HEPARINUM [Pedobacter heparinus] |
| 1HM2_A | 8.74e-67 | 686 | 1291 | 54 | 661 | ACTIVESITE OF CHONDROITINASE AC LYASE REVEALED BY THE STRUCTURE OF ENZYME-OLIGOSACCHARIDE COMPLEXES AND MUTAGENESIS [Pedobacter heparinus],1HM3_A Active Site Of Chondroitinase Ac Lyase Revealed By The Structure Of Enzyme-Oligosaccharide Complexes And Mutagenesis [Pedobacter heparinus],1HMU_A ACTIVE SITE OF CHONDROITINASE AC LYASE REVEALED BY THE STRUCTURE OF ENZYME-OLIGOSACCHARIDE COMPLEXES AND MUTAGENESIS [Pedobacter heparinus],1HMW_A Active Site Of Chondroitinase Ac Lyase Revealed By The Structure Of Enzyme-oligosaccharide Complexes And Mutagenesis [Pedobacter heparinus] |
| 6F2P_A | 6.64e-47 | 695 | 1307 | 58 | 713 | Structureof Paenibacillus xanthan lyase to 2.6 A resolution [Paenibacillus] |
| 2E24_A | 1.57e-46 | 689 | 1260 | 37 | 668 | ChainA, Xanthan lyase [Bacillus sp. GL1] |
| 2E22_A | 2.80e-46 | 689 | 1260 | 37 | 668 | Crystalstructure of xanthan lyase in complex with mannose [Bacillus sp. GL1] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q59288 | 4.78e-66 | 686 | 1291 | 54 | 661 | Chondroitinase-AC OS=Pedobacter heparinus (strain ATCC 13125 / DSM 2366 / CIP 104194 / JCM 7457 / NBRC 12017 / NCIMB 9290 / NRRL B-14731 / HIM 762-3) OX=485917 GN=cslA PE=1 SV=1 |
| Q9AQS0 | 6.21e-45 | 689 | 1260 | 62 | 693 | Xanthan lyase OS=Bacillus sp. (strain GL1) OX=84635 GN=xly PE=1 SV=1 |
| P38536 | 1.29e-33 | 1812 | 2140 | 1544 | 1857 | Amylopullulanase OS=Thermoanaerobacterium thermosulfurigenes OX=33950 GN=amyB PE=3 SV=2 |
| Q9GUC9 | 9.93e-26 | 240 | 472 | 27 | 274 | Uncharacterized protein F14F9.5 OS=Caenorhabditis elegans OX=6239 GN=F14F9.5 PE=1 SV=2 |
| P38535 | 4.36e-23 | 1965 | 2140 | 907 | 1083 | Exoglucanase XynX OS=Acetivibrio thermocellus OX=1515 GN=xynX PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000317 | 0.998973 | 0.000211 | 0.000181 | 0.000165 | 0.000152 |