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CAZyme Information: MGYG000001543_02131
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Lachnoclostridium sp900078195 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; Lachnoclostridium; Lachnoclostridium sp900078195 | |||||||||||
| CAZyme ID | MGYG000001543_02131 | |||||||||||
| CAZy Family | GH5 | |||||||||||
| CAZyme Description | hypothetical protein | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 525949; End: 527925 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH5 | 65 | 344 | 3.3e-83 | 0.9927536231884058 |
| CBM46 | 373 | 458 | 2.2e-25 | 0.9885057471264368 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam00150 | Cellulase | 2.36e-43 | 61 | 345 | 12 | 271 | Cellulase (glycosyl hydrolase family 5). |
| pfam18448 | CBM46 | 6.00e-29 | 463 | 562 | 2 | 102 | Carbohydrate binding domain. Carbohydrate active enzymes (CAZYmes) that target recalcitrant polysaccharides are modular enzymes containing noncatalytic carbohydrate-binding modules (CBMs) that direct enzymes to their cognate substrate, thus potentiating catalysis. The structure of Bacillus halodurans endo-beta-1,4-glucanase B (Cel5B) reveals that CBM46 is tightly associated with the catalytic module and, dependent on the glucan presented to the enzyme, can contribute directly to substrate binding or play a targeting role in directing the enzyme to regions of the plant cell wall rich in the polysaccharide hydrolyzed by the enzyme. The CBM46 domain displays a classic beta-sandwich jelly roll fold. Against beta-1,3-1,4-glucans CBM46 domain participates in productive substrate binding and thus plays a direct role in the hydrolytic activity of the enzyme. |
| COG2730 | BglC | 2.50e-28 | 44 | 354 | 51 | 371 | Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism]. |
| pfam03442 | CBM_X2 | 1.93e-14 | 373 | 458 | 2 | 83 | Carbohydrate binding domain X2. This domain binds to cellulose and to bacterial cell walls. It is found in glycosyl hydrolases and in scaffolding proteins of cellulosomes (multiprotein glycosyl hydrolase complexes). In the cellulosome it may aid cellulose degradation by anchoring the cellulosome to the bacterial cell wall and by binding it to its substrate. This domain has an Ig-like fold. |
| PRK11198 | PRK11198 | 2.73e-14 | 580 | 657 | 62 | 145 | LysM domain/BON superfamily protein; Provisional |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AUS96699.1 | 8.39e-259 | 4 | 549 | 4 | 550 |
| BCN31364.1 | 1.54e-250 | 5 | 552 | 5 | 559 |
| ADL52313.1 | 4.81e-240 | 5 | 562 | 5 | 566 |
| BAV13065.1 | 4.81e-240 | 5 | 562 | 5 | 566 |
| ACZ98603.1 | 7.11e-229 | 1 | 576 | 1 | 574 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 4V2X_A | 1.62e-164 | 12 | 562 | 33 | 581 | ChainA, Endo-beta-1,4-glucanase (cellulase B) [Halalkalibacterium halodurans] |
| 5XRC_A | 3.58e-160 | 21 | 562 | 30 | 566 | ATrimodular GH5_4 Subfamily Endoglucanase Structure with Large Unit Cell [Bacillus sp. BG-CS10],5XRC_B A Trimodular GH5_4 Subfamily Endoglucanase Structure with Large Unit Cell [Bacillus sp. BG-CS10],5XRC_C A Trimodular GH5_4 Subfamily Endoglucanase Structure with Large Unit Cell [Bacillus sp. BG-CS10] |
| 5E0C_A | 4.22e-160 | 29 | 562 | 5 | 533 | StructuralInsight of a Trimodular Halophilic Cellulase with a Family 46 Carbohydrate-Binding Module [Bacillus sp. BG-CS10] |
| 5E09_A | 2.20e-154 | 29 | 562 | 5 | 533 | StructuralInsight of a Trimodular Halophilic Cellulase with a Family 46 Carbohydrate-Binding Module [Bacillus sp. BG-CS10] |
| 4YZP_A | 2.90e-74 | 22 | 541 | 9 | 532 | Crystalstructure of a tri-modular GH5 (subfamily 4) endo-beta-1, 4-glucanase from Bacillus licheniformis [Bacillus licheniformis],4YZT_A Crystal structure of a tri-modular GH5 (subfamily 4) endo-beta-1, 4-glucanase from Bacillus licheniformis complexed with cellotetraose [Bacillus licheniformis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P23550 | 2.85e-165 | 5 | 562 | 8 | 561 | Endoglucanase B OS=Paenibacillus lautus OX=1401 GN=celB PE=3 SV=1 |
| P23660 | 3.29e-46 | 44 | 347 | 34 | 335 | Endoglucanase A OS=Ruminococcus albus OX=1264 GN=celA PE=1 SV=1 |
| P28623 | 8.08e-46 | 44 | 343 | 50 | 339 | Endoglucanase D OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=engD PE=1 SV=2 |
| P10477 | 1.66e-44 | 5 | 345 | 2 | 354 | Cellulase/esterase CelE OS=Acetivibrio thermocellus (strain ATCC 27405 / DSM 1237 / JCM 9322 / NBRC 103400 / NCIMB 10682 / NRRL B-4536 / VPI 7372) OX=203119 GN=celE PE=1 SV=2 |
| P28621 | 4.34e-44 | 25 | 343 | 31 | 341 | Endoglucanase B OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=engB PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000249 | 0.998988 | 0.000294 | 0.000167 | 0.000154 | 0.000140 |
