logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000001633_02040

You are here: Home > Sequence: MGYG000001633_02040

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species RC9 sp000435075
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; UBA932; RC9; RC9 sp000435075
CAZyme ID MGYG000001633_02040
CAZy Family GH2
CAZyme Description Beta-galactosidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
987 MGYG000001633_51|CGC1 110520.18 5.0673
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000001633 2721018 MAG China Asia
Gene Location Start: 757;  End: 3720  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000001633_02040.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH2 45 522 4.6e-97 0.523936170212766

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd09019 galactose_mutarotase_like 1.19e-159 654 984 1 326
galactose mutarotase_like. Galactose mutarotase catalyzes the conversion of beta-D-galactose to alpha-D-galactose. Beta-D-galactose is produced by the degradation of lactose, a disaccharide composed of beta-D-glucose and beta-D-galactose. This epimerization reaction is the first step in the four-step Leloir pathway, which converts galactose into metabolically important glucose. This epimerization step is followed by the phosophorylation of alpha-D-galactose by galactokinase, an enzyme which can only act on the alpha anomer. A glutamate and a histidine residue of the galactose mutarotase have been shown to be critical for catalysis, the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen. Galactose mutarotase is a member of the aldose-1-epimerase superfamily.
PLN00194 PLN00194 4.51e-122 654 986 11 337
aldose 1-epimerase; Provisional
PRK11055 galM 4.08e-95 653 986 10 341
galactose-1-epimerase; Provisional
pfam01263 Aldose_epim 1.63e-81 654 983 2 300
Aldose 1-epimerase.
COG2017 GalM 4.65e-64 649 987 9 308
Galactose mutarotase or related enzyme [Carbohydrate transport and metabolism].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ABR42251.1 2.96e-217 1 625 1 601
QRO17549.1 2.96e-217 1 625 1 601
AST54135.1 5.92e-217 1 625 1 601
QUT94725.1 5.92e-217 1 625 1 601
BBK91716.1 5.92e-217 1 625 1 601

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
7SF2_A 8.42e-199 22 625 4 585
ChainA, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_B Chain B, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_C Chain C, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_D Chain D, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_E Chain E, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838],7SF2_F Chain F, Glycosyl hydrolase family 2, sugar binding domain protein [Bacteroides cellulosilyticus DSM 14838]
1SNZ_A 8.82e-78 655 986 24 343
Crystalstructure of apo human galactose mutarotase [Homo sapiens],1SNZ_B Crystal structure of apo human galactose mutarotase [Homo sapiens],1SO0_A Crystal structure of human galactose mutarotase complexed with galactose [Homo sapiens],1SO0_B Crystal structure of human galactose mutarotase complexed with galactose [Homo sapiens],1SO0_C Crystal structure of human galactose mutarotase complexed with galactose [Homo sapiens],1SO0_D Crystal structure of human galactose mutarotase complexed with galactose [Homo sapiens]
4RNL_A 6.19e-69 655 987 25 343
Thecrystal structure of a possible galactose mutarotase from Streptomyces platensis subsp. rosaceus [Streptomyces platensis],4RNL_B The crystal structure of a possible galactose mutarotase from Streptomyces platensis subsp. rosaceus [Streptomyces platensis],4RNL_C The crystal structure of a possible galactose mutarotase from Streptomyces platensis subsp. rosaceus [Streptomyces platensis],4RNL_D The crystal structure of a possible galactose mutarotase from Streptomyces platensis subsp. rosaceus [Streptomyces platensis]
1LUR_A 2.85e-43 662 985 23 336
CrystalStructure of the GalM/aldose Epimerase Homologue from C. elegans, Northeast Structural Genomics Target WR66 [Caenorhabditis elegans],1LUR_B Crystal Structure of the GalM/aldose Epimerase Homologue from C. elegans, Northeast Structural Genomics Target WR66 [Caenorhabditis elegans]
1L7J_A 1.63e-35 653 987 13 339
ChainA, galactose mutarotase [Lactococcus lactis],1L7J_B Chain B, galactose mutarotase [Lactococcus lactis],1L7K_A Chain A, galactose mutarotase [Lactococcus lactis],1L7K_B Chain B, galactose mutarotase [Lactococcus lactis],1MMU_A Chain A, Aldose 1-epimerase [Lactococcus lactis],1MMU_B Chain B, Aldose 1-epimerase [Lactococcus lactis],1MMX_A Chain A, Aldose 1-epimerase [Lactococcus lactis],1MMX_B Chain B, Aldose 1-epimerase [Lactococcus lactis],1MMY_A Chain A, Aldose 1-epimerase [Lactococcus lactis],1MMY_B Chain B, Aldose 1-epimerase [Lactococcus lactis],1MMZ_A Chain A, Aldose 1-epimerase [Lactococcus lactis],1MMZ_B Chain B, Aldose 1-epimerase [Lactococcus lactis],1MN0_A Chain A, Aldose 1-epimerase [Lactococcus lactis],1MN0_B Chain B, Aldose 1-epimerase [Lactococcus lactis]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q66HG4 1.27e-79 655 986 22 341
Galactose mutarotase OS=Rattus norvegicus OX=10116 GN=Galm PE=1 SV=1
Q8K157 1.76e-79 655 986 22 341
Galactose mutarotase OS=Mus musculus OX=10090 GN=Galm PE=1 SV=1
P05149 1.09e-77 652 987 37 380
Aldose 1-epimerase OS=Acinetobacter calcoaceticus OX=471 GN=mro PE=1 SV=1
Q5EA79 4.54e-77 655 986 22 341
Galactose mutarotase OS=Bos taurus OX=9913 GN=GALM PE=2 SV=1
Q96C23 4.54e-77 655 986 22 341
Galactose mutarotase OS=Homo sapiens OX=9606 GN=GALM PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000947 0.641730 0.356658 0.000247 0.000210 0.000202

TMHMM  Annotations      download full data without filtering help

start end
5 24