Chitinase, GH18 family [Carbohydrate transport and metabolism].

The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an eight-stranded alpha/beta barrel with a pronounced active-site cleft at the C-terminal end of the beta-barrel.

Glyco_18 domain.

Glycosyl hydrolases family 18.

Chitinase A, N-terminal domain. This domain is found in a number of bacterial chitinases and similar viral proteins. It is organized into a fibronectin III module domain-like fold, comprising only beta strands. Its function is not known, but it may be involved in interaction with the enzyme substrate, chitin. It is separated by a hinge region from the catalytic domain (pfam00704); this hinge region is probably mobile, allowing the N-terminal domain to have different relative positions in solution.

ChainA, Chitinase A [Vibrio harveyi],3B9D_A Chain A, Chitinase A [Vibrio harveyi],3B9E_A Chain A, Chitinase A [Vibrio harveyi]

CrystalStructure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - apo structure [Vibrio harveyi],3ARP_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with DEQUALINIUM [Vibrio harveyi],3ARQ_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with IDARUBICIN [Vibrio harveyi],3ARR_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with PENTOXIFYLLINE [Vibrio harveyi],3ARV_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Sanguinarine [Vibrio harveyi],3ARW_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with chelerythrine [Vibrio harveyi],3ARX_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with Propentofylline [Vibrio harveyi],3ARY_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with 2-(imidazolin-2-yl)-5-isothiocyanatobenzofuran [Vibrio harveyi],3ARZ_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - complex structure with 2-(imidazolin-2-yl)-5-isothiocyanatobenzofuran [Vibrio harveyi],3B8S_A Crystal structure of wild-type chitinase A from Vibrio harveyi [Vibrio harveyi],3B8S_B Crystal structure of wild-type chitinase A from Vibrio harveyi [Vibrio harveyi]

CrystalStructure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - apo structure of mutant W275G [Vibrio harveyi],3ART_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with DEQUALINIUM [Vibrio harveyi],3ARU_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with PENTOXIFYLLINE [Vibrio harveyi],3AS0_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with Sanguinarine [Vibrio harveyi],3AS1_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with chelerythrine [Vibrio harveyi],3AS2_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with Propentofylline [Vibrio harveyi],3AS3_A Crystal Structure Analysis of Chitinase A from Vibrio harveyi with novel inhibitors - W275G mutant complex structure with 2-(imidazolin-2-yl)-5-isothiocyanatobenzofuran [Vibrio harveyi]

ChitinaseA from Serratia marcescens ATCC990 in complex with Chitotrio-thiazoline dithioamide. [Serratia marcescens]

ChitinaseA from Serratia marcescens ATCC990 in complex with Chitotrio-thiazoline. [Serratia marcescens],2WLZ_A Chitinase A from Serratia marcescens ATCC990 in complex with Chitobio- thiazoline. [Serratia marcescens],2WM0_A Chitinase A from Serratia marcescens ATCC990 in complex with Chitobio- thiazoline thioamide. [Serratia marcescens]

Chitinase A OS=Pseudoalteromonas piscicida OX=43662 GN=chiA PE=1 SV=1

Chitinase A OS=Serratia marcescens OX=615 GN=chiA PE=1 SV=3

Chitinase OS=Autographa californica nuclear polyhedrosis virus OX=46015 GN=CHIA PE=1 SV=1

Probable endochitinase OS=Orgyia pseudotsugata multicapsid polyhedrosis virus OX=262177 GN=ORF124 PE=3 SV=1

Chitinase A1 OS=Niallia circulans OX=1397 GN=chiA1 PE=1 SV=1