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CAZyme Information: MGYG000001859_00217
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_C; Negativicutes; Acidaminococcales; Acidaminococcaceae; Phascolarctobacterium_A; | |||||||||||
| CAZyme ID | MGYG000001859_00217 | |||||||||||
| CAZy Family | GH23 | |||||||||||
| CAZyme Description | Endo-type membrane-bound lytic murein transglycosylase A | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 23902; End: 24441 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH23 | 37 | 168 | 2e-27 | 0.8222222222222222 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd16896 | LT_Slt70-like | 2.84e-76 | 25 | 169 | 2 | 146 | uncharacterized lytic transglycosylase subfamily with similarity to Slt70. Uncharacterized lytic transglycosylase (LT) with a conserved sequence pattern suggesting similarity to the Slt70, a 70kda soluble lytic transglycosylase which also has an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| cd13401 | Slt70-like | 4.29e-54 | 27 | 175 | 6 | 150 | 70kDa soluble lytic transglycosylase (Slt70) and similar proteins. Catalytic domain of the 70kda soluble lytic transglycosylase (LT)-like proteins, which also have an N-terminal U-shaped U-domain and a linker L-domain. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Proteins similar to this family include the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda. |
| cd00254 | LT-like | 3.45e-35 | 42 | 165 | 1 | 108 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
| COG0741 | MltE | 2.42e-31 | 26 | 179 | 138 | 292 | Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell wall/membrane/envelope biogenesis]. |
| pfam01464 | SLT | 1.68e-28 | 34 | 141 | 4 | 108 | Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QTV76946.1 | 1.19e-113 | 7 | 179 | 34 | 206 |
| BBG64618.1 | 1.16e-89 | 9 | 179 | 29 | 199 |
| QNP77119.1 | 9.69e-89 | 9 | 179 | 40 | 210 |
| ADB46849.1 | 1.15e-65 | 12 | 175 | 30 | 193 |
| AEQ23289.1 | 3.98e-61 | 11 | 174 | 30 | 193 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5MPQ_A | 1.54e-24 | 23 | 174 | 412 | 559 | BulgecinA: The key to a broad-spectrum inhibitor that targets lytic transglycosylases [Neisseria meningitidis] |
| 5O1J_A | 1.55e-24 | 23 | 174 | 416 | 563 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
| 6FPN_B | 1.56e-24 | 23 | 174 | 422 | 569 | Lytictransglycosylase in action [Neisseria meningitidis MC58] |
| 5O24_A | 1.57e-24 | 23 | 174 | 426 | 573 | Lytictransglycosylase in action [Neisseria meningitidis] |
| 5O29_A | 1.58e-24 | 23 | 174 | 432 | 579 | Lytictransglycosylase in action [Neisseria meningitidis] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P39434 | 1.53e-18 | 10 | 171 | 467 | 625 | Soluble lytic murein transglycosylase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=slt PE=3 SV=2 |
| P44888 | 6.01e-17 | 47 | 177 | 448 | 578 | Putative soluble lytic murein transglycosylase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=slt PE=3 SV=1 |
| P0AGC4 | 2.10e-16 | 10 | 171 | 467 | 625 | Soluble lytic murein transglycosylase OS=Escherichia coli O157:H7 OX=83334 GN=slt PE=3 SV=1 |
| P0AGC3 | 2.10e-16 | 10 | 171 | 467 | 625 | Soluble lytic murein transglycosylase OS=Escherichia coli (strain K12) OX=83333 GN=slt PE=1 SV=1 |
| O64046 | 2.83e-15 | 23 | 169 | 1418 | 1543 | Probable tape measure protein OS=Bacillus phage SPbeta OX=66797 GN=yomI PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000031 | 0.000004 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |