Species | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Dialisteraceae; ; | |||||||||||
CAZyme ID | MGYG000002053_00133 | |||||||||||
CAZy Family | GT83 | |||||||||||
CAZyme Description | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 2637; End: 4241 Strand: + |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT83 | 11 | 411 | 2e-91 | 0.7685185185185185 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
COG1807 | ArnT | 8.64e-41 | 10 | 416 | 9 | 422 | 4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis]. |
PRK13279 | arnT | 9.15e-26 | 3 | 341 | 2 | 343 | lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase. |
pfam13231 | PMT_2 | 3.40e-13 | 64 | 225 | 1 | 159 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366. |
pfam02366 | PMT | 5.14e-07 | 1 | 231 | 2 | 240 | Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
BBK24579.1 | 1.15e-179 | 14 | 530 | 32 | 548 |
AOH39318.1 | 6.33e-166 | 10 | 532 | 11 | 536 |
AXB83023.1 | 8.55e-132 | 10 | 509 | 6 | 513 |
BBU37212.1 | 2.01e-121 | 15 | 530 | 11 | 534 |
QQB17174.1 | 5.17e-119 | 15 | 530 | 11 | 534 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
5EZM_A | 2.88e-18 | 18 | 276 | 41 | 302 | CrystalStructure of ArnT from Cupriavidus metallidurans in the apo state [Cupriavidus metallidurans CH34],5F15_A Crystal Structure of ArnT from Cupriavidus metallidurans bound to Undecaprenyl phosphate [Cupriavidus metallidurans CH34] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
O67270 | 1.60e-26 | 12 | 316 | 6 | 305 | Uncharacterized protein aq_1220 OS=Aquifex aeolicus (strain VF5) OX=224324 GN=aq_1220 PE=3 SV=1 |
Q1CIH9 | 2.61e-24 | 33 | 329 | 31 | 331 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pestis bv. Antiqua (strain Nepal516) OX=377628 GN=arnT PE=3 SV=1 |
B2K5L1 | 2.61e-24 | 33 | 329 | 31 | 331 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) OX=502801 GN=arnT PE=3 SV=1 |
Q1C744 | 2.61e-24 | 33 | 329 | 31 | 331 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pestis bv. Antiqua (strain Antiqua) OX=360102 GN=arnT PE=3 SV=1 |
A4TIM6 | 2.61e-24 | 33 | 329 | 31 | 331 | Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia pestis (strain Pestoides F) OX=386656 GN=arnT PE=3 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
0.979714 | 0.016552 | 0.003177 | 0.000053 | 0.000034 | 0.000489 |
start | end |
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7 | 26 |
67 | 86 |
93 | 110 |
114 | 133 |
140 | 157 |
172 | 194 |
207 | 229 |
259 | 278 |
291 | 310 |
314 | 336 |
343 | 365 |
369 | 387 |
394 | 416 |
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