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CAZyme Information: MGYG000002141_00051
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | CAG-95 sp900554925 | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes_A; Clostridia; Lachnospirales; Lachnospiraceae; CAG-95; CAG-95 sp900554925 | |||||||||||
| CAZyme ID | MGYG000002141_00051 | |||||||||||
| CAZy Family | GT11 | |||||||||||
| CAZyme Description | O-antigen biosynthesis glycosyltransferase WbnK | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 54273; End: 55121 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT11 | 1 | 267 | 2.4e-71 | 0.9420289855072463 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd11301 | Fut1_Fut2_like | 2.64e-68 | 1 | 266 | 1 | 258 | Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. |
| pfam01531 | Glyco_transf_11 | 1.10e-29 | 1 | 260 | 1 | 276 | Glycosyl transferase family 11. This family contains several fucosyl transferase enzymes. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| SNX52916.1 | 5.58e-73 | 1 | 271 | 1 | 276 |
| QUO20851.1 | 2.48e-68 | 1 | 262 | 1 | 264 |
| AOZ97425.1 | 1.48e-65 | 1 | 271 | 1 | 279 |
| QTL97698.1 | 3.89e-65 | 1 | 281 | 1 | 275 |
| AIT08976.1 | 7.03e-64 | 1 | 274 | 1 | 273 |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q58YV9 | 1.44e-35 | 6 | 278 | 5 | 300 | O-antigen biosynthesis glycosyltransferase WbnK OS=Escherichia coli OX=562 GN=wbnK PE=1 SV=1 |
| Q866D6 | 4.59e-08 | 109 | 249 | 149 | 317 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Leontopithecus chrysomelas OX=57374 GN=FUT1 PE=3 SV=1 |
| P19526 | 8.25e-08 | 109 | 249 | 149 | 317 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Homo sapiens OX=9606 GN=FUT1 PE=1 SV=1 |
| Q9TUD6 | 8.27e-08 | 109 | 249 | 150 | 318 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Pan troglodytes OX=9598 GN=FUT1 PE=3 SV=1 |
| Q866F0 | 1.49e-07 | 109 | 249 | 150 | 318 | Galactoside alpha-(1,2)-fucosyltransferase 1 OS=Saimiri boliviensis boliviensis OX=39432 GN=FUT1 PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000058 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |