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CAZyme Information: MGYG000002168_01178

You are here: Home > Sequence: MGYG000002168_01178

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Prevotella sp900556825
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Prevotella; Prevotella sp900556825
CAZyme ID MGYG000002168_01178
CAZy Family GH29
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
476 MGYG000002168_24|CGC2 54834.81 9.1259
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002168 3553249 MAG Denmark Europe
Gene Location Start: 19645;  End: 21075  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002168_01178.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH29 32 377 5.2e-89 0.9248554913294798

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
smart00812 Alpha_L_fucos 6.60e-114 28 413 1 381
Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis.
pfam01120 Alpha_L_fucos 7.68e-87 43 371 15 331
Alpha-L-fucosidase.
COG3669 AfuC 6.76e-38 60 377 1 321
Alpha-L-fucosidase [Carbohydrate transport and metabolism].
pfam14871 GHL6 2.77e-04 107 183 1 82
Hypothetical glycosyl hydrolase 6. GHL6 is a family of hypothetical glycoside hydrolases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QUU07337.1 1.85e-260 5 476 7 480
ASM65412.1 5.49e-260 30 476 35 481
QQT78056.1 5.49e-260 30 476 35 481
QRP56700.1 5.49e-260 30 476 35 481
QCQ35262.1 1.24e-256 27 476 23 472

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
4JL2_A 2.73e-249 30 476 2 450
Crystalstructure of a bacterial fucosidase with a monovalent iminocyclitol inhibitor [Bacteroides thetaiotaomicron VPI-5482],4JL2_B Crystal structure of a bacterial fucosidase with a monovalent iminocyclitol inhibitor [Bacteroides thetaiotaomicron VPI-5482]
2XIB_A 4.32e-249 27 476 2 453
CrystalStructure Of An Alpha-L-Fucosidase Gh29 From Bacteroides Thetaiotaomicron In Complex With Deoxyfuconojirimycin [Bacteroides thetaiotaomicron],2XIB_B Crystal Structure Of An Alpha-L-Fucosidase Gh29 From Bacteroides Thetaiotaomicron In Complex With Deoxyfuconojirimycin [Bacteroides thetaiotaomicron],2XIB_C Crystal Structure Of An Alpha-L-Fucosidase Gh29 From Bacteroides Thetaiotaomicron In Complex With Deoxyfuconojirimycin [Bacteroides thetaiotaomicron],2XIB_D Crystal Structure Of An Alpha-L-Fucosidase Gh29 From Bacteroides Thetaiotaomicron In Complex With Deoxyfuconojirimycin [Bacteroides thetaiotaomicron],2XII_A Crystal Structure Of An Alpha-L-Fucosidase Gh29 From Bacteroides Thetaiotaomicron In Complex With An Extended 9- Fluorenone Iminosugar Inhibitor [Bacteroides thetaiotaomicron],2XII_B Crystal Structure Of An Alpha-L-Fucosidase Gh29 From Bacteroides Thetaiotaomicron In Complex With An Extended 9- Fluorenone Iminosugar Inhibitor [Bacteroides thetaiotaomicron]
6HZY_A 4.82e-249 11 476 10 475
Crystalstructure of a bacterial fucosidase with inhibitor FucPUG [Bacteroides thetaiotaomicron VPI-5482],6HZY_B Crystal structure of a bacterial fucosidase with inhibitor FucPUG [Bacteroides thetaiotaomicron VPI-5482]
2WVV_B 7.80e-249 30 476 2 450
Crystalstructure of an alpha-L-fucosidase GH29 from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482]
2WVV_A 1.11e-248 30 476 2 450
Crystalstructure of an alpha-L-fucosidase GH29 from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2WVV_C Crystal structure of an alpha-L-fucosidase GH29 from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],2WVV_D Crystal structure of an alpha-L-fucosidase GH29 from Bacteroides thetaiotaomicron [Bacteroides thetaiotaomicron VPI-5482],4J27_A Crystal structure of a gh29 alpha-l-fucosidase gh29 from bacteroides thetaiotaomicron in a novel crystal form [Bacteroides thetaiotaomicron VPI-5482],4J27_B Crystal structure of a gh29 alpha-l-fucosidase gh29 from bacteroides thetaiotaomicron in a novel crystal form [Bacteroides thetaiotaomicron VPI-5482],4J28_A Crystal structure of a gh29 alpha-l-fucosidase gh29 from bacteroides thetaiotaomicron in complex with a 5-membered iminocyclitol inhibitor [Bacteroides thetaiotaomicron VPI-5482],4J28_B Crystal structure of a gh29 alpha-l-fucosidase gh29 from bacteroides thetaiotaomicron in complex with a 5-membered iminocyclitol inhibitor [Bacteroides thetaiotaomicron VPI-5482],4JFS_A Crystal structure of a bacterial fucosidase with iminosugar inhibitor 4-epi-(+)-Codonopsinine [Bacteroides thetaiotaomicron VPI-5482],4JFS_B Crystal structure of a bacterial fucosidase with iminosugar inhibitor 4-epi-(+)-Codonopsinine [Bacteroides thetaiotaomicron VPI-5482],4JFT_A Crystal structure of a bacterial fucosidase with iminosugar inhibitor N-desmethyl-4-epi-(+)-Codonopsinine [Bacteroides thetaiotaomicron VPI-5482],4JFT_B Crystal structure of a bacterial fucosidase with iminosugar inhibitor N-desmethyl-4-epi-(+)-Codonopsinine [Bacteroides thetaiotaomicron VPI-5482],4JFU_A Crystal structure of a bacterial fucosidase with iminosugar inhibitor [Bacteroides thetaiotaomicron VPI-5482],4JFU_B Crystal structure of a bacterial fucosidase with iminosugar inhibitor [Bacteroides thetaiotaomicron VPI-5482],4JFV_A Crystal structure of a bacterial fucosidase with iminosugar inhibitor (2S,3S,4R,5S)-2-[N-(methylferrocene)]aminoethyl-5-methylpyrrolidine-3,4-diol [Bacteroides thetaiotaomicron VPI-5482],4JFV_B Crystal structure of a bacterial fucosidase with iminosugar inhibitor (2S,3S,4R,5S)-2-[N-(methylferrocene)]aminoethyl-5-methylpyrrolidine-3,4-diol [Bacteroides thetaiotaomicron VPI-5482],4JFV_C Crystal structure of a bacterial fucosidase with iminosugar inhibitor (2S,3S,4R,5S)-2-[N-(methylferrocene)]aminoethyl-5-methylpyrrolidine-3,4-diol [Bacteroides thetaiotaomicron VPI-5482],4JFV_D Crystal structure of a bacterial fucosidase with iminosugar inhibitor (2S,3S,4R,5S)-2-[N-(methylferrocene)]aminoethyl-5-methylpyrrolidine-3,4-diol [Bacteroides thetaiotaomicron VPI-5482],4JFW_A Crystal structure of a bacterial fucosidase with iminosugar inhibitor (2S,3S,4R,5S)-2-[N-(propylferrocene)]aminoethyl-5-methylpyrrolidine-3,4-diol [Bacteroides thetaiotaomicron VPI-5482],4JFW_B Crystal structure of a bacterial fucosidase with iminosugar inhibitor (2S,3S,4R,5S)-2-[N-(propylferrocene)]aminoethyl-5-methylpyrrolidine-3,4-diol [Bacteroides thetaiotaomicron VPI-5482],4JFW_C Crystal structure of a bacterial fucosidase with iminosugar inhibitor (2S,3S,4R,5S)-2-[N-(propylferrocene)]aminoethyl-5-methylpyrrolidine-3,4-diol [Bacteroides thetaiotaomicron VPI-5482],4JFW_D Crystal structure of a bacterial fucosidase with iminosugar inhibitor (2S,3S,4R,5S)-2-[N-(propylferrocene)]aminoethyl-5-methylpyrrolidine-3,4-diol [Bacteroides thetaiotaomicron VPI-5482],4JL1_A Crystal structure of a bacterial fucosidase with a multivalent iminocyclitol inhibitor [Bacteroides thetaiotaomicron VPI-5482],4JL1_B Crystal structure of a bacterial fucosidase with a multivalent iminocyclitol inhibitor [Bacteroides thetaiotaomicron VPI-5482]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P17164 1.50e-37 43 466 42 459
Tissue alpha-L-fucosidase OS=Rattus norvegicus OX=10116 GN=Fuca1 PE=1 SV=1
P48300 1.07e-36 43 430 46 427
Tissue alpha-L-fucosidase OS=Canis lupus familiaris OX=9615 GN=FUCA1 PE=2 SV=1
P04066 2.07e-36 10 466 13 463
Tissue alpha-L-fucosidase OS=Homo sapiens OX=9606 GN=FUCA1 PE=1 SV=4
Q99LJ1 2.29e-36 43 466 32 449
Tissue alpha-L-fucosidase OS=Mus musculus OX=10090 GN=Fuca1 PE=1 SV=1
Q2KIM0 7.61e-36 43 430 49 428
Tissue alpha-L-fucosidase OS=Bos taurus OX=9913 GN=FUCA1 PE=2 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.342373 0.643235 0.005973 0.002804 0.002232 0.003357

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002168_01178.