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CAZyme Information: MGYG000002249_01033
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Firmicutes; Bacilli; RF39; UBA660; UBA5026; | |||||||||||
| CAZyme ID | MGYG000002249_01033 | |||||||||||
| CAZy Family | GT51 | |||||||||||
| CAZyme Description | Penicillin-binding protein 2D | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 143; End: 1435 Strand: + | |||||||||||
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| TIGR02074 | PBP_1a_fam | 4.85e-99 | 1 | 370 | 165 | 531 | penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan] |
| COG0744 | MrcB | 8.53e-97 | 1 | 370 | 240 | 599 | Membrane carboxypeptidase (penicillin-binding protein) [Cell wall/membrane/envelope biogenesis]. |
| COG5009 | MrcA | 1.47e-65 | 1 | 413 | 230 | 764 | Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]. |
| PRK11636 | mrcA | 1.76e-39 | 86 | 413 | 424 | 828 | penicillin-binding protein 1a; Provisional |
| COG0768 | FtsI | 1.42e-26 | 5 | 320 | 181 | 528 | Cell division protein FtsI/penicillin-binding protein 2 [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QVK17409.1 | 5.69e-118 | 1 | 413 | 234 | 649 |
| AEH49664.1 | 4.22e-116 | 1 | 413 | 237 | 653 |
| APM79991.1 | 8.39e-116 | 1 | 413 | 237 | 653 |
| ANZ29253.1 | 8.39e-116 | 1 | 413 | 237 | 653 |
| ALF09171.1 | 8.39e-116 | 1 | 413 | 237 | 653 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3ZG8_B | 9.86e-33 | 1 | 343 | 82 | 433 | CrystalStructure of Penicillin Binding Protein 4 from Listeria monocytogenes in the Ampicillin bound form [Listeria monocytogenes],3ZG9_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Cefuroxime bound form [Listeria monocytogenes],3ZGA_B Crystal Structure of Penicillin-Binding Protein 4 from Listeria monocytogenes in the Carbenicillin bound form [Listeria monocytogenes] |
| 4OON_A | 5.42e-32 | 88 | 392 | 395 | 747 | Crystalstructure of PBP1a in complex with compound 17 ((4Z,8S,11E,14S)-5-(2-amino-1,3-thiazol-4-yl)-14-(5,6-dihydroxy-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-8-formyl-2-methyl-6-oxo-3,10-dioxa-4,7,11-triazatetradeca-4,11-diene-2,12,14-tricarboxylic acid) [Pseudomonas aeruginosa PAO1] |
| 2JCH_A | 1.25e-30 | 14 | 353 | 24 | 361 | Structuraland mechanistic basis of penicillin binding protein inhibition by lactivicins [Streptococcus pneumoniae R6] |
| 2XD1_A | 3.33e-30 | 35 | 353 | 76 | 392 | ACTIVESITE RESTRUCTURING REGULATES LIGAND RECOGNITION IN CLASS A PENICILLIN-BINDING PROTEINS [Streptococcus pneumoniae R6],2XD1_B ACTIVE SITE RESTRUCTURING REGULATES LIGAND RECOGNITION IN CLASS A PENICILLIN-BINDING PROTEINS [Streptococcus pneumoniae R6] |
| 2BG1_A | 3.33e-30 | 35 | 353 | 76 | 392 | Activesite restructuring regulates ligand recognition in classA Penicillin-binding proteins (PBPs) [Streptococcus pneumoniae R6],2XD5_A Structural insights into the catalytic mechanism and the role of Streptococcus pneumoniae PBP1b [Streptococcus pneumoniae R6],2XD5_B Structural insights into the catalytic mechanism and the role of Streptococcus pneumoniae PBP1b [Streptococcus pneumoniae R6] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P70997 | 2.02e-98 | 36 | 415 | 272 | 655 | Penicillin-binding protein 2D OS=Bacillus subtilis (strain 168) OX=224308 GN=pbpG PE=2 SV=3 |
| O66874 | 2.58e-40 | 1 | 414 | 226 | 713 | Penicillin-binding protein 1A OS=Aquifex aeolicus (strain VF5) OX=224324 GN=mrcA PE=1 SV=1 |
| Q9KNU5 | 7.76e-34 | 90 | 413 | 434 | 803 | Penicillin-binding protein 1A OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) OX=243277 GN=mrcA PE=3 SV=2 |
| Q92G78 | 1.48e-32 | 59 | 394 | 385 | 743 | Penicillin-binding protein 1A OS=Rickettsia conorii (strain ATCC VR-613 / Malish 7) OX=272944 GN=mrcA PE=3 SV=1 |
| Q4UK08 | 4.91e-32 | 59 | 394 | 385 | 743 | Penicillin-binding protein 1A OS=Rickettsia felis (strain ATCC VR-1525 / URRWXCal2) OX=315456 GN=mrcA PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000049 | 0.000001 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |