Species | Staphylococcus aureus | |||||||||||
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Lineage | Bacteria; Firmicutes; Bacilli; Staphylococcales; Staphylococcaceae; Staphylococcus; Staphylococcus aureus | |||||||||||
CAZyme ID | MGYG000002337_02423 | |||||||||||
CAZy Family | GH23 | |||||||||||
CAZyme Description | putative transglycosylase IsaA | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 2573600; End: 2574301 Strand: - |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
cd13925 | RPF | 6.53e-07 | 174 | 232 | 1 | 69 | core lysozyme-like domain of resuscitation-promoting factor proteins. Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF. |
pfam01464 | SLT | 5.86e-05 | 166 | 204 | 5 | 43 | Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems. |
cd00254 | LT-like | 1.78e-04 | 177 | 207 | 5 | 35 | lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. |
cd00442 | Lyz-like | 0.001 | 175 | 221 | 1 | 58 | lysozyme-like domains. This family contains several members, including soluble lytic transglycosylases (SLT), goose egg-white lysozymes (GEWL), hen egg-white lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, chitosanases, and pesticin. Typical members are involved in the hydrolysis of beta-1,4- linked polysaccharides. |
pfam06737 | Transglycosylas | 0.004 | 173 | 231 | 2 | 72 | Transglycosylase-like domain. This family of proteins are very likely to act as transglycosylase enzymes related to pfam00062 and pfam01464. These other families are weakly matched by this family, and include the known active site residues. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
QBS28062.1 | 2.20e-159 | 1 | 233 | 1 | 233 |
BAS52624.1 | 2.20e-159 | 1 | 233 | 1 | 233 |
QSU59838.1 | 2.20e-159 | 1 | 233 | 1 | 233 |
QCV69228.1 | 2.20e-159 | 1 | 233 | 1 | 233 |
AXP69747.1 | 2.20e-159 | 1 | 233 | 1 | 233 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
Q2FV52 | 4.41e-160 | 1 | 233 | 1 | 233 | Probable transglycosylase IsaA OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=isaA PE=1 SV=1 |
P60158 | 4.41e-160 | 1 | 233 | 1 | 233 | Probable transglycosylase IsaA OS=Staphylococcus aureus OX=1280 GN=isaA PE=1 SV=1 |
Q2FDT8 | 4.41e-160 | 1 | 233 | 1 | 233 | Probable transglycosylase IsaA OS=Staphylococcus aureus (strain USA300) OX=367830 GN=isaA PE=3 SV=1 |
A6QK59 | 4.41e-160 | 1 | 233 | 1 | 233 | Probable transglycosylase IsaA OS=Staphylococcus aureus (strain Newman) OX=426430 GN=isaA PE=3 SV=1 |
Q5HCY1 | 4.41e-160 | 1 | 233 | 1 | 233 | Probable transglycosylase IsaA OS=Staphylococcus aureus (strain COL) OX=93062 GN=isaA PE=1 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
0.000286 | 0.998905 | 0.000181 | 0.000228 | 0.000195 | 0.000172 |
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