logo
sublogo
You are browsing environment: HUMAN GUT
help

CAZyme Information: MGYG000002337_02423

You are here: Home > Sequence: MGYG000002337_02423

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Staphylococcus aureus
Lineage Bacteria; Firmicutes; Bacilli; Staphylococcales; Staphylococcaceae; Staphylococcus; Staphylococcus aureus
CAZyme ID MGYG000002337_02423
CAZy Family GH23
CAZyme Description putative transglycosylase IsaA
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
233 MGYG000002337_1|CGC24 24203.2 6.6029
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002337 2749621 Isolate not provided not provided
Gene Location Start: 2573600;  End: 2574301  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002337_02423.

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd13925 RPF 6.53e-07 174 232 1 69
core lysozyme-like domain of resuscitation-promoting factor proteins. Resuscitation-promoting factor (RPF) proteins, found in various (G+C)-rich Gram-positive bacteria, act to reactivate cultures from stationary phase. This protein shares elements of the structural core of lysozyme and related proteins. Furthermore, it shares a conserved active site glutamate which is required for activity, and has a polysaccharide binding cleft that corresponds to the peptidoglycan binding cleft of lysozyme. Muralytic activity of Rpf in Micrococcus luteus correlates with resuscitation, supporting a mechanism dependent on cleavage of peptidoglycan by RPF.
pfam01464 SLT 5.86e-05 166 204 5 43
Transglycosylase SLT domain. This family is distantly related to pfam00062. Members are found in phages, type II, type III and type IV secretion systems.
cd00254 LT-like 1.78e-04 177 207 5 35
lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.
cd00442 Lyz-like 0.001 175 221 1 58
lysozyme-like domains. This family contains several members, including soluble lytic transglycosylases (SLT), goose egg-white lysozymes (GEWL), hen egg-white lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, chitosanases, and pesticin. Typical members are involved in the hydrolysis of beta-1,4- linked polysaccharides.
pfam06737 Transglycosylas 0.004 173 231 2 72
Transglycosylase-like domain. This family of proteins are very likely to act as transglycosylase enzymes related to pfam00062 and pfam01464. These other families are weakly matched by this family, and include the known active site residues.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QBS28062.1 2.20e-159 1 233 1 233
BAS52624.1 2.20e-159 1 233 1 233
QSU59838.1 2.20e-159 1 233 1 233
QCV69228.1 2.20e-159 1 233 1 233
AXP69747.1 2.20e-159 1 233 1 233

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q2FV52 4.41e-160 1 233 1 233
Probable transglycosylase IsaA OS=Staphylococcus aureus (strain NCTC 8325 / PS 47) OX=93061 GN=isaA PE=1 SV=1
P60158 4.41e-160 1 233 1 233
Probable transglycosylase IsaA OS=Staphylococcus aureus OX=1280 GN=isaA PE=1 SV=1
Q2FDT8 4.41e-160 1 233 1 233
Probable transglycosylase IsaA OS=Staphylococcus aureus (strain USA300) OX=367830 GN=isaA PE=3 SV=1
A6QK59 4.41e-160 1 233 1 233
Probable transglycosylase IsaA OS=Staphylococcus aureus (strain Newman) OX=426430 GN=isaA PE=3 SV=1
Q5HCY1 4.41e-160 1 233 1 233
Probable transglycosylase IsaA OS=Staphylococcus aureus (strain COL) OX=93062 GN=isaA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000286 0.998905 0.000181 0.000228 0.000195 0.000172

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002337_02423.