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CAZyme Information: MGYG000002359_03085

You are here: Home > Sequence: MGYG000002359_03085

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Mycobacterium tuberculosis
Lineage Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis
CAZyme ID MGYG000002359_03085
CAZy Family GT1
CAZyme Description PGL/p-HBAD biosynthesis glycosyltransferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
428 46795.94 9.3822
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002359 4387829 Isolate Sweden Europe
Gene Location Start: 188883;  End: 190169  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002359_03085.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT1 35 409 2.6e-41 0.9240837696335078

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG1819 YjiC 2.10e-123 30 428 1 399
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism].
cd03784 GT1_Gtf-like 4.27e-36 32 426 2 404
UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.
TIGR01426 MGT 1.76e-13 240 409 201 373
glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]
cd03785 GT28_MurG 3.95e-13 32 406 1 339
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
COG0707 MurG 1.86e-12 78 427 47 355
UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AMC43197.1 0.0 1 428 1 428
APR58266.1 0.0 1 428 1 428
AIH71596.1 0.0 1 428 1 428
ACT24058.1 0.0 1 428 1 428
ALB20164.1 0.0 1 428 1 428

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3OTG_A 5.22e-19 205 412 177 397
CrystalStructure of CalG1, Calicheamicin Glycostyltransferase, TDP bound form [Micromonospora echinospora],3OTH_A Crystal Structure of CalG1, Calicheamicin Glycostyltransferase, TDP and calicheamicin alpha3I bound form [Micromonospora echinospora],3OTH_B Crystal Structure of CalG1, Calicheamicin Glycostyltransferase, TDP and calicheamicin alpha3I bound form [Micromonospora echinospora]
6KQW_A 4.09e-07 265 397 219 356
ChainA, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168]
6KQX_A 4.14e-07 265 397 219 356
ChainA, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168],7BOV_A Chain A, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168]
3UYK_A 9.20e-06 202 407 165 368
SpinosynRhamnosyltransferase SpnG complexed with spinosyn aglycone [Saccharopolyspora spinosa],3UYK_B Spinosyn Rhamnosyltransferase SpnG complexed with spinosyn aglycone [Saccharopolyspora spinosa],3UYL_A Spinosyn Rhamnosyltransferase SpnG complexed with thymidine diphosphate [Saccharopolyspora spinosa],3UYL_B Spinosyn Rhamnosyltransferase SpnG complexed with thymidine diphosphate [Saccharopolyspora spinosa]
3TSA_A 9.27e-06 202 407 165 368
SpinosynRhamnosyltransferase SpnG [Saccharopolyspora spinosa],3TSA_B Spinosyn Rhamnosyltransferase SpnG [Saccharopolyspora spinosa]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P9WFR1 0.0 1 428 1 428
PGL/p-HBAD biosynthesis glycosyltransferase Rv2958c OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=Rv2958c PE=1 SV=1
P9WFR0 0.0 1 428 1 428
PGL/p-HBAD biosynthesis glycosyltransferase MT3034 OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=MT3034 PE=3 SV=1
A5U6W6 0.0 1 428 1 428
PGL/p-HBAD biosynthesis glycosyltransferase MRA_2985 OS=Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) OX=419947 GN=MRA_2985 PE=3 SV=1
P9WN09 1.16e-237 13 427 25 438
PGL/p-HBAD biosynthesis rhamnosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=Rv2962c PE=1 SV=1
Q7TXJ4 1.16e-237 13 427 25 438
PGL/p-HBAD biosynthesis rhamnosyltransferase OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=BQ2027_MB2986C PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000013 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002359_03085.