Species | Mycobacterium tuberculosis | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Lineage | Bacteria; Actinobacteriota; Actinomycetia; Mycobacteriales; Mycobacteriaceae; Mycobacterium; Mycobacterium tuberculosis | |||||||||||
CAZyme ID | MGYG000002359_03085 | |||||||||||
CAZy Family | GT1 | |||||||||||
CAZyme Description | PGL/p-HBAD biosynthesis glycosyltransferase | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 188883; End: 190169 Strand: - |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT1 | 35 | 409 | 2.6e-41 | 0.9240837696335078 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
COG1819 | YjiC | 2.10e-123 | 30 | 428 | 1 | 399 | UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism]. |
cd03784 | GT1_Gtf-like | 4.27e-36 | 32 | 426 | 2 | 404 | UDP-glycosyltransferases and similar proteins. This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. |
TIGR01426 | MGT | 1.76e-13 | 240 | 409 | 201 | 373 | glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance] |
cd03785 | GT28_MurG | 3.95e-13 | 32 | 406 | 1 | 339 | undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
COG0707 | MurG | 1.86e-12 | 78 | 427 | 47 | 355 | UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell wall/membrane/envelope biogenesis]. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
AMC43197.1 | 0.0 | 1 | 428 | 1 | 428 |
APR58266.1 | 0.0 | 1 | 428 | 1 | 428 |
AIH71596.1 | 0.0 | 1 | 428 | 1 | 428 |
ACT24058.1 | 0.0 | 1 | 428 | 1 | 428 |
ALB20164.1 | 0.0 | 1 | 428 | 1 | 428 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
3OTG_A | 5.22e-19 | 205 | 412 | 177 | 397 | CrystalStructure of CalG1, Calicheamicin Glycostyltransferase, TDP bound form [Micromonospora echinospora],3OTH_A Crystal Structure of CalG1, Calicheamicin Glycostyltransferase, TDP and calicheamicin alpha3I bound form [Micromonospora echinospora],3OTH_B Crystal Structure of CalG1, Calicheamicin Glycostyltransferase, TDP and calicheamicin alpha3I bound form [Micromonospora echinospora] |
6KQW_A | 4.09e-07 | 265 | 397 | 219 | 356 | ChainA, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168] |
6KQX_A | 4.14e-07 | 265 | 397 | 219 | 356 | ChainA, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168],7BOV_A Chain A, Uncharacterized UDP-glucosyltransferase YjiC [Bacillus subtilis subsp. subtilis str. 168] |
3UYK_A | 9.20e-06 | 202 | 407 | 165 | 368 | SpinosynRhamnosyltransferase SpnG complexed with spinosyn aglycone [Saccharopolyspora spinosa],3UYK_B Spinosyn Rhamnosyltransferase SpnG complexed with spinosyn aglycone [Saccharopolyspora spinosa],3UYL_A Spinosyn Rhamnosyltransferase SpnG complexed with thymidine diphosphate [Saccharopolyspora spinosa],3UYL_B Spinosyn Rhamnosyltransferase SpnG complexed with thymidine diphosphate [Saccharopolyspora spinosa] |
3TSA_A | 9.27e-06 | 202 | 407 | 165 | 368 | SpinosynRhamnosyltransferase SpnG [Saccharopolyspora spinosa],3TSA_B Spinosyn Rhamnosyltransferase SpnG [Saccharopolyspora spinosa] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
P9WFR1 | 0.0 | 1 | 428 | 1 | 428 | PGL/p-HBAD biosynthesis glycosyltransferase Rv2958c OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=Rv2958c PE=1 SV=1 |
P9WFR0 | 0.0 | 1 | 428 | 1 | 428 | PGL/p-HBAD biosynthesis glycosyltransferase MT3034 OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=MT3034 PE=3 SV=1 |
A5U6W6 | 0.0 | 1 | 428 | 1 | 428 | PGL/p-HBAD biosynthesis glycosyltransferase MRA_2985 OS=Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) OX=419947 GN=MRA_2985 PE=3 SV=1 |
P9WN09 | 1.16e-237 | 13 | 427 | 25 | 438 | PGL/p-HBAD biosynthesis rhamnosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=Rv2962c PE=1 SV=1 |
Q7TXJ4 | 1.16e-237 | 13 | 427 | 25 | 438 | PGL/p-HBAD biosynthesis rhamnosyltransferase OS=Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) OX=233413 GN=BQ2027_MB2986C PE=3 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
1.000013 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
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