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CAZyme Information: MGYG000002431_01218
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Campylobacter_A concisus_I | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Campylobacterota; Campylobacteria; Campylobacterales; Campylobacteraceae; Campylobacter_A; Campylobacter_A concisus_I | |||||||||||
| CAZyme ID | MGYG000002431_01218 | |||||||||||
| CAZy Family | GT9 | |||||||||||
| CAZyme Description | ADP-heptose--LPS heptosyltransferase 2 | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 37190; End: 38134 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT9 | 66 | 291 | 2.4e-52 | 0.9733333333333334 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd03789 | GT9_LPS_heptosyltransferase | 1.04e-61 | 2 | 306 | 1 | 276 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
| COG0859 | RfaF | 8.40e-59 | 1 | 311 | 2 | 332 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
| TIGR02195 | heptsyl_trn_II | 9.04e-43 | 2 | 308 | 1 | 332 | lipopolysaccharide heptosyltransferase II. This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| pfam01075 | Glyco_transf_9 | 3.12e-35 | 65 | 288 | 2 | 244 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
| PRK10916 | PRK10916 | 1.01e-20 | 152 | 273 | 187 | 307 | ADP-heptose--LPS heptosyltransferase RfaF. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QPH83978.1 | 4.61e-222 | 1 | 314 | 1 | 314 |
| QPH98962.1 | 9.30e-222 | 1 | 314 | 1 | 314 |
| QPI00758.1 | 9.30e-222 | 1 | 314 | 1 | 314 |
| QPH85854.1 | 5.38e-221 | 1 | 314 | 1 | 314 |
| ALF47139.1 | 1.48e-218 | 1 | 314 | 1 | 314 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 1PSW_A | 5.13e-17 | 143 | 308 | 178 | 342 | Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli] |
| 3TOV_A | 8.05e-09 | 2 | 264 | 10 | 299 | Thecrystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008],3TOV_B The crystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| P45042 | 1.13e-19 | 1 | 310 | 1 | 346 | ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1 |
| P37692 | 1.73e-17 | 143 | 308 | 178 | 342 | ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1 |
| P37421 | 8.16e-17 | 143 | 305 | 178 | 339 | ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1 |
| Q57336 | 2.56e-06 | 145 | 265 | 177 | 294 | Lipopolysaccharide core heptosyltransferase OpsX OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=opsX PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000091 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |