Species | Cronobacter malonaticus | |||||||||||
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Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Cronobacter; Cronobacter malonaticus | |||||||||||
CAZyme ID | MGYG000002484_00198 | |||||||||||
CAZy Family | GT9 | |||||||||||
CAZyme Description | Lipopolysaccharide core heptosyltransferase RfaQ | |||||||||||
CAZyme Property |
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Genome Property |
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Gene Location | Start: 28981; End: 29982 Strand: + |
Family | Start | End | Evalue | family coverage |
---|---|---|---|---|
GT9 | 62 | 296 | 4e-58 | 0.8977777777777778 |
Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
---|---|---|---|---|---|---|---|
TIGR02201 | heptsyl_trn_III | 3.06e-176 | 1 | 333 | 13 | 344 | lipopolysaccharide heptosyltransferase III, putative. This family consists of examples of the putative ADP-heptose:LPS heptosyltransferase III, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. This enzyme may be less widely distributed than heptosyltransferases I and II. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
PRK10422 | PRK10422 | 1.52e-112 | 1 | 332 | 19 | 343 | lipopolysaccharide core biosynthesis protein; Provisional |
COG0859 | RfaF | 2.16e-76 | 1 | 333 | 15 | 331 | ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis]. |
cd03789 | GT9_LPS_heptosyltransferase | 5.22e-75 | 1 | 330 | 13 | 277 | lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. |
pfam01075 | Glyco_transf_9 | 4.13e-54 | 61 | 303 | 2 | 236 | Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core. |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
---|---|---|---|---|---|
AHB72388.1 | 7.09e-251 | 1 | 333 | 27 | 359 |
ALX80407.1 | 7.09e-251 | 1 | 333 | 27 | 359 |
AMO46554.1 | 1.80e-214 | 1 | 333 | 27 | 358 |
ALB64581.1 | 9.40e-196 | 1 | 333 | 27 | 357 |
AKL14527.1 | 2.55e-184 | 1 | 333 | 27 | 358 |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
3TOV_A | 6.68e-17 | 1 | 332 | 22 | 345 | Thecrystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008],3TOV_B The crystal structure of the glycosyl transferase family 9 from Veillonella parvula DSM 2008 [Veillonella parvula DSM 2008] |
1PSW_A | 2.81e-10 | 7 | 293 | 20 | 305 | Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli] |
Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
---|---|---|---|---|---|---|
Q9R9D5 | 2.78e-87 | 1 | 332 | 7 | 331 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli OX=562 GN=rfaQ PE=1 SV=1 |
P25742 | 3.15e-87 | 1 | 332 | 7 | 331 | Lipopolysaccharide core heptosyltransferase RfaQ OS=Escherichia coli (strain K12) OX=83333 GN=rfaQ PE=3 SV=2 |
Q57336 | 2.90e-19 | 8 | 293 | 29 | 299 | Lipopolysaccharide core heptosyltransferase OpsX OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=opsX PE=3 SV=1 |
P37692 | 2.50e-11 | 1 | 293 | 14 | 305 | ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1 |
P37421 | 8.14e-11 | 1 | 293 | 14 | 305 | ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1 |
Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
---|---|---|---|---|---|
1.000077 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |
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