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CAZyme Information: MGYG000002489_00701
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | Neisseria gonorrhoeae | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Burkholderiales; Neisseriaceae; Neisseria; Neisseria gonorrhoeae | |||||||||||
| CAZyme ID | MGYG000002489_00701 | |||||||||||
| CAZy Family | GT19 | |||||||||||
| CAZyme Description | Lipid-A-disaccharide synthase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 78321; End: 79475 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT19 | 9 | 366 | 7.1e-130 | 0.9915254237288136 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| PRK00025 | lpxB | 2.35e-175 | 9 | 380 | 4 | 373 | lipid-A-disaccharide synthase; Reviewed |
| COG0763 | LpxB | 4.95e-175 | 7 | 384 | 2 | 381 | Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis]. |
| pfam02684 | LpxB | 6.83e-114 | 9 | 378 | 1 | 374 | Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide. |
| TIGR00215 | lpxB | 4.24e-108 | 4 | 380 | 3 | 384 | lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| PRK01021 | lpxB | 5.31e-48 | 11 | 342 | 231 | 566 | lipid-A-disaccharide synthase; Reviewed |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| AKP15183.1 | 1.75e-275 | 1 | 384 | 1 | 384 |
| QBK55025.1 | 1.75e-275 | 1 | 384 | 1 | 384 |
| SNU85101.1 | 1.75e-275 | 1 | 384 | 1 | 384 |
| SBO56395.1 | 1.75e-275 | 1 | 384 | 1 | 384 |
| SBQ22999.1 | 1.75e-275 | 1 | 384 | 1 | 384 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5W8N_A | 8.77e-94 | 1 | 382 | 1 | 381 | LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)] |
| 5W8S_A | 1.24e-93 | 1 | 382 | 1 | 381 | LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q5F5Y6 | 4.39e-276 | 1 | 384 | 7 | 390 | Lipid-A-disaccharide synthase OS=Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) OX=242231 GN=lpxB PE=3 SV=1 |
| Q9K1F5 | 2.95e-268 | 1 | 384 | 1 | 384 | Lipid-A-disaccharide synthase OS=Neisseria meningitidis serogroup B (strain MC58) OX=122586 GN=lpxB PE=3 SV=2 |
| A1KRN0 | 1.20e-267 | 1 | 384 | 1 | 384 | Lipid-A-disaccharide synthase OS=Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM 15464 / FAM18) OX=272831 GN=lpxB PE=3 SV=1 |
| Q9JX45 | 1.10e-263 | 1 | 384 | 1 | 384 | Lipid-A-disaccharide synthase OS=Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491) OX=122587 GN=lpxB PE=3 SV=1 |
| Q7NVY1 | 9.58e-141 | 1 | 384 | 1 | 385 | Lipid-A-disaccharide synthase OS=Chromobacterium violaceum (strain ATCC 12472 / DSM 30191 / JCM 1249 / NBRC 12614 / NCIMB 9131 / NCTC 9757) OX=243365 GN=lpxB PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000041 | 0.000000 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |