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CAZyme Information: MGYG000002489_00944

You are here: Home > Sequence: MGYG000002489_00944

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Neisseria gonorrhoeae
Lineage Bacteria; Proteobacteria; Gammaproteobacteria; Burkholderiales; Neisseriaceae; Neisseria; Neisseria gonorrhoeae
CAZyme ID MGYG000002489_00944
CAZy Family GT25
CAZyme Description Lipooligosaccharide biosynthesis protein lex-1
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
279 MGYG000002489_6|CGC1 31794.38 6.572
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002489 2153911 Isolate Canada North America
Gene Location Start: 59009;  End: 59848  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.1.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT25 2 185 1.6e-35 0.9834254143646409

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
COG3306 COG3306 3.59e-80 1 256 3 246
Glycosyltransferase involved in LPS biosynthesis, GR25 family [Cell wall/membrane/envelope biogenesis].
pfam01755 Glyco_transf_25 1.82e-68 2 185 3 200
Glycosyltransferase family 25 (LPS biosynthesis protein). Members of this family belong to Glycosyltransferase family 25 This is a family of glycosyltransferases involved in lipopolysaccharide (LPS) biosynthesis. These enzymes catalyze the transfer of various sugars onto the growing LPS chain during its biosynthesis.
cd06532 Glyco_transf_25 1.39e-31 2 185 1 128
Glycosyltransferase family 25 [lipooligosaccharide (LOS) biosynthesis protein] is a family of glycosyltransferases involved in LOS biosynthesis. The members include the beta(1,4) galactosyltransferases: Lgt2 of Moraxella catarrhalis, LgtB and LgtE of Neisseria gonorrhoeae and Lic2A of Haemophilus influenzae. M. catarrhalis Lgt2 catalyzes the addition of galactose (Gal) to the growing chain of LOS on the cell surface. N. gonorrhoeae LgtB and LgtE link Gal-beta(1,4) to GlcNAc (N-acetylglucosamine) and Glc (glucose), respectively. The genes encoding LgtB and LgtE are two genes of a five gene locus involved in the synthesis of gonococcal LOS. LgtE is believed to perform the first step in LOS biosynthesis.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
SNV87650.1 7.27e-206 1 279 1 279
SNU85321.1 7.27e-206 1 279 1 279
ASQ74736.1 7.27e-206 1 279 1 279
ASQ72417.1 7.27e-206 1 279 1 279
SBO73894.1 7.27e-206 1 279 1 279

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q50947 9.43e-203 1 279 1 279
Lacto-N-neotetraose biosynthesis glycosyltransferase LgtB OS=Neisseria gonorrhoeae OX=485 GN=lgtB PE=3 SV=1
P57033 6.73e-187 1 279 1 279
Lacto-N-neotetraose biosynthesis glycosyltransferase LgtB OS=Neisseria meningitidis serogroup A / serotype 4A (strain DSM 15465 / Z2491) OX=122587 GN=lgtB PE=3 SV=1
Q51116 8.84e-182 1 279 1 275
Lacto-N-neotetraose biosynthesis glycosyltransferase LgtB OS=Neisseria meningitidis serogroup B (strain MC58) OX=122586 GN=lgtB PE=3 SV=2
Q50950 1.47e-142 1 278 1 279
Lacto-N-neotetraose biosynthesis glycosyltransferase LgtE OS=Neisseria gonorrhoeae OX=485 GN=lgtE PE=3 SV=1
Q51117 4.34e-123 1 278 1 279
Lacto-N-neotetraose biosynthesis glycosyltransferase LgtE OS=Neisseria meningitidis serogroup B (strain MC58) OX=122586 GN=lgtE PE=3 SV=2

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000064 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002489_00944.