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CAZyme Information: MGYG000002505_00156

You are here: Home > Sequence: MGYG000002505_00156

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Oxalobacter formigenes_B
Lineage Bacteria; Proteobacteria; Gammaproteobacteria; Burkholderiales; Burkholderiaceae; Oxalobacter; Oxalobacter formigenes_B
CAZyme ID MGYG000002505_00156
CAZy Family GT9
CAZyme Description ADP-heptose--LPS heptosyltransferase 2
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
366 MGYG000002505_1|CGC1 40981.83 9.3663
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002505 2465390 Isolate not provided North America
Gene Location Start: 184285;  End: 185385  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

EC 2.4.99.-

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT9 77 327 3.7e-61 0.9822222222222222

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
TIGR02195 heptsyl_trn_II 5.14e-142 10 346 1 334
lipopolysaccharide heptosyltransferase II. This family consists of examples of ADP-heptose:LPS heptosyltransferase II, an enzyme of LPS inner core region biosynthesis. LPS, composed of lipid A, a core region, and O antigen, is found in the outer membrane of Gram-negative bacteria. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]
PRK10916 PRK10916 9.94e-97 10 345 2 343
ADP-heptose--LPS heptosyltransferase RfaF.
COG0859 RfaF 2.67e-83 10 345 3 330
ADP-heptose:LPS heptosyltransferase [Cell wall/membrane/envelope biogenesis].
cd03789 GT9_LPS_heptosyltransferase 3.98e-75 10 343 1 277
lipopolysaccharide heptosyltransferase and similar proteins. Lipopolysaccharide heptosyltransferase (2.4.99.B6) is involved in the biosynthesis of lipooligosaccharide (LOS). Lipopolysaccharide (LPS) is a major component of the outer membrane of gram-negative bacteria. LPS heptosyltransferase transfers heptose molecules from ADP-heptose to 3-deoxy-D-manno-octulosonic acid (KDO), a part of the inner core component of LPS. This family also contains lipopolysaccharide 1,2-N-acetylglucosaminetransferase EC 2.4.1.56 and belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.
pfam01075 Glyco_transf_9 6.18e-60 77 325 1 245
Glycosyltransferase family 9 (heptosyltransferase). Members of this family belong to glycosyltransferase family 9. Lipopolysaccharide is a major component of the outer leaflet of the outer membrane in Gram-negative bacteria. It is composed of three domains; lipid A, Core oligosaccharide and the O-antigen. All of these enzymes transfer heptose to the lipopolysaccharide core.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QDX34123.1 5.04e-159 7 343 1 337
ARQ46794.1 5.22e-159 7 343 2 338
ARQ78855.1 5.22e-159 7 343 2 338
BBB67613.1 1.48e-141 9 357 10 352
BBB61552.1 1.97e-139 9 345 10 344

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1PSW_A 2.27e-71 10 346 2 344
Structureof E. coli ADP-heptose lps heptosyltransferase II [Escherichia coli]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P37421 2.53e-76 10 345 2 343
ADP-heptose--LPS heptosyltransferase 2 OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=rfaF PE=3 SV=1
P37692 1.01e-75 10 346 2 344
ADP-heptose--LPS heptosyltransferase 2 OS=Escherichia coli (strain K12) OX=83333 GN=rfaF PE=1 SV=1
P45042 1.84e-69 10 345 2 344
ADP-heptose--LPS heptosyltransferase 2 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=rfaF PE=3 SV=1
Q57336 4.35e-11 1 309 1 301
Lipopolysaccharide core heptosyltransferase OpsX OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=opsX PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000052 0.000000 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002505_00156.