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CAZyme Information: MGYG000002584_00746

You are here: Home > Sequence: MGYG000002584_00746

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Akkermansia sp900545155
Lineage Bacteria; Verrucomicrobiota; Verrucomicrobiae; Verrucomicrobiales; Akkermansiaceae; Akkermansia; Akkermansia sp900545155
CAZyme ID MGYG000002584_00746
CAZy Family GH63
CAZyme Description Cytoplasmic trehalase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
566 MGYG000002584_4|CGC1 65085.96 6.6048
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002584 3044716 MAG China Asia
Gene Location Start: 180372;  End: 182072  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002584_00746.

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam01204 Trehalase 3.67e-21 305 479 326 497
Trehalase. Trehalase (EC:3.2.1.28) is known to recycle trehalose to glucose. Trehalose is a physiological hallmark of heat-shock response in yeast and protects of proteins and membranes against a variety of stresses. This family is found in conjunction with pfam07492 in fungi.
PRK10137 PRK10137 8.20e-18 305 434 599 744
alpha-glucosidase; Provisional
pfam03200 Glyco_hydro_63 9.68e-16 146 493 178 493
Glycosyl hydrolase family 63 C-terminal domain. This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63. They catalyze the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC:3.2.1.106 is the first enzyme in the N-linked oligosaccharide processing pathway. This family represents the C-terminal catalytic domain.
COG1626 TreA 5.38e-15 70 435 157 498
Neutral trehalase [Carbohydrate transport and metabolism].
PRK13270 treF 8.00e-11 297 463 362 518
alpha,alpha-trehalase TreF.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QAT91813.1 2.94e-188 33 565 35 507
QWP09187.1 4.02e-188 33 565 4 476
QWP15489.1 4.02e-188 33 565 4 476
QWP35628.1 4.02e-188 33 565 4 476
QWP56518.1 4.02e-188 33 565 4 476

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
3W7S_A 4.72e-08 251 438 522 714
Escherichiacoli K12 YgjK complexed with glucose [Escherichia coli K-12],3W7S_B Escherichia coli K12 YgjK complexed with glucose [Escherichia coli K-12],3W7T_A Escherichia coli K12 YgjK complexed with mannose [Escherichia coli K-12],3W7T_B Escherichia coli K12 YgjK complexed with mannose [Escherichia coli K-12],3W7U_A Escherichia coli K12 YgjK complexed with galactose [Escherichia coli K-12],3W7U_B Escherichia coli K12 YgjK complexed with galactose [Escherichia coli K-12]
3W7W_A 4.72e-08 251 438 522 714
Crystalstructure of E. coli YgjK E727A complexed with 2-O-alpha-D-glucopyranosyl-alpha-D-galactopyranose [Escherichia coli K-12],3W7W_B Crystal structure of E. coli YgjK E727A complexed with 2-O-alpha-D-glucopyranosyl-alpha-D-galactopyranose [Escherichia coli K-12],5GW7_A Crystal structure of the glycosynthase mutant E727A of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12],5GW7_B Crystal structure of the glycosynthase mutant E727A of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12]
3W7X_A 4.72e-08 251 438 522 714
Crystalstructure of E. coli YgjK D324N complexed with melibiose [Escherichia coli K-12],3W7X_B Crystal structure of E. coli YgjK D324N complexed with melibiose [Escherichia coli K-12],5CA3_A Crystal structure of the glycosynthase mutant D324N of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12],5CA3_B Crystal structure of the glycosynthase mutant D324N of Escherichia coli GH63 glycosidase in complex with glucose and lactose [Escherichia coli K-12]
6XUX_A 5.03e-08 251 438 71 263
ChainA, Nanobody,Glucosidase YgjK,Glucosidase YgjK,Nanobody [Escherichia coli K-12]
7PQQ_B 5.03e-08 251 438 71 263
ChainB, Anti-RON nanobody,Megabody 91,Glucosidase YgjK [Lama glama]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P94250 9.41e-20 284 508 180 407
Uncharacterized protein BB_0381 OS=Borreliella burgdorferi (strain ATCC 35210 / DSM 4680 / CIP 102532 / B31) OX=224326 GN=BB_0381 PE=4 SV=2
O42783 5.87e-10 303 433 513 645
Cytosolic neutral trehalase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) OX=367110 GN=treB PE=2 SV=2
J5K1E2 8.50e-08 305 433 514 644
Cytosolic neutral trehalase OS=Beauveria bassiana (strain ARSEF 2860) OX=655819 GN=NTH1 PE=1 SV=1
C0Q162 9.49e-08 297 479 362 535
Cytoplasmic trehalase OS=Salmonella paratyphi C (strain RKS4594) OX=476213 GN=treF PE=3 SV=1
Q8ZLC8 9.49e-08 297 479 362 535
Cytoplasmic trehalase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) OX=99287 GN=treF PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.001137 0.925105 0.072949 0.000304 0.000253 0.000229

TMHMM  Annotations      help

There is no transmembrane helices in MGYG000002584_00746.