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CAZyme Information: MGYG000002585_00293
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; Bacteroides; | |||||||||||
| CAZyme ID | MGYG000002585_00293 | |||||||||||
| CAZy Family | GH30 | |||||||||||
| CAZyme Description | Cellobiose 2-epimerase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 67193; End: 70264 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH30 | 671 | 1020 | 1.5e-18 | 0.7553956834532374 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| pfam07221 | GlcNAc_2-epim | 6.88e-48 | 57 | 389 | 1 | 330 | N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase). This family contains a number of eukaryotic and bacterial N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) enzymes (EC:5.3.1.8) approximately 500 residues long. This converts N-acyl-D-glucosamine to N-acyl-D-mannosamine. |
| cd00249 | AGE | 2.60e-47 | 25 | 404 | 1 | 369 | AGE domain; N-acyl-D-glucosamine 2-epimerase domain; Responsible for intermediate epimerization during biosynthesis of N-acetylneuraminic acid. Catalytic mechanism is believed to be via nucleotide elimination and readdition and is ATP modulated. AGE is structurally and mechanistically distinct from the other four types of epimerases. The AGE domain monomer is composed of an alpha(6)/alpha(6)-barrel, the structure of which is also found in glucoamylase and cellulase. The active form is a homodimer. The alignment also contains subtype III mannose 6-phosphate isomerases. |
| COG2942 | YihS | 1.04e-46 | 21 | 389 | 1 | 357 | Mannose or cellobiose epimerase, N-acyl-D-glucosamine 2-epimerase family [Carbohydrate transport and metabolism]. |
| COG5520 | XynC | 3.05e-13 | 603 | 1020 | 35 | 427 | O-Glycosyl hydrolase [Cell wall/membrane/envelope biogenesis]. |
| COG1331 | YyaL | 1.47e-06 | 78 | 189 | 412 | 517 | Uncharacterized conserved protein YyaL, SSP411 family, contains thoiredoxin and six-hairpin glycosidase-like domains [General function prediction only]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QNE42320.1 | 3.29e-172 | 417 | 1021 | 6 | 641 |
| CDZ25110.1 | 2.28e-71 | 31 | 417 | 5 | 383 |
| AQG78206.1 | 2.77e-06 | 621 | 1020 | 57 | 440 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 3WKF_A | 4.31e-97 | 29 | 420 | 13 | 406 | Crystalstructure of cellobiose 2-epimerase [Rhodothermus marinus],3WKG_A Crystal structure of cellobiose 2-epimerase in complex with glucosylmannose [Rhodothermus marinus],3WKH_A Crystal structure of cellobiose 2-epimerase in complex with epilactose [Rhodothermus marinus],3WKI_A Crystal structure of cellobiose 2-epimerase in complex with cellobiitol [Rhodothermus marinus] |
| 5ZHB_A | 1.20e-83 | 30 | 416 | 3 | 388 | ChainA, Cellobiose 2-epimerase [Caldibacillus thermoamylovorans],5ZHB_B Chain B, Cellobiose 2-epimerase [Caldibacillus thermoamylovorans] |
| 7D5G_A | 8.27e-83 | 33 | 416 | 8 | 389 | ChainA, Cellobiose 2-epimerase [Caldicellulosiruptor saccharolyticus DSM 8903] |
| 4Z4J_A | 1.22e-82 | 33 | 416 | 20 | 401 | CrystalStructure of cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus DSM 8903 [Caldicellulosiruptor saccharolyticus DSM 8903] |
| 4Z4L_A | 3.18e-81 | 33 | 416 | 20 | 401 | CrystalStructure of cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus DSM 8903 [Caldicellulosiruptor saccharolyticus DSM 8903] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q5LH66 | 9.86e-105 | 31 | 412 | 5 | 389 | Cellobiose 2-epimerase OS=Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) OX=272559 GN=bfce PE=1 SV=1 |
| F8WRK9 | 2.36e-96 | 29 | 420 | 13 | 406 | Cellobiose 2-epimerase OS=Rhodothermus marinus OX=29549 GN=ce PE=1 SV=1 |
| E6UB41 | 2.80e-76 | 34 | 415 | 5 | 385 | Cellobiose 2-epimerase OS=Ruminococcus albus (strain ATCC 27210 / DSM 20455 / JCM 14654 / NCDO 2250 / 7) OX=697329 GN=Rumal_0019 PE=3 SV=1 |
| B8DZK4 | 3.86e-76 | 27 | 416 | 2 | 389 | Cellobiose 2-epimerase OS=Dictyoglomus turgidum (strain DSM 6724 / Z-1310) OX=515635 GN=Dtur_0652 PE=1 SV=1 |
| P0DKY4 | 1.87e-74 | 34 | 415 | 5 | 385 | Cellobiose 2-epimerase OS=Ruminococcus albus OX=1264 GN=ce-ne1 PE=1 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000192 | 0.999193 | 0.000164 | 0.000155 | 0.000146 | 0.000138 |