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CAZyme Information: MGYG000002656_01263

You are here: Home > Sequence: MGYG000002656_01263

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species F23-B02 sp900772725
Lineage Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Oscillospiraceae; F23-B02; F23-B02 sp900772725
CAZyme ID MGYG000002656_01263
CAZy Family GT39
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
580 65590.4 7.1901
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002656 1621357 MAG United Republic of Tanzania Africa
Gene Location Start: 938;  End: 2680  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002656_01263.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT39 190 384 6.7e-55 0.9147982062780269

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
pfam16192 PMT_4TMC 9.22e-25 409 576 7 198
C-terminal four TMM region of protein-O-mannosyltransferase. PMT_4TMC is the C-terminal four membrane-pass region of protein-O-mannosyltransferases and similar enzymes.
COG1928 PMT1 1.34e-16 190 382 46 265
Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].
pfam13231 PMT_2 2.76e-16 216 377 1 160
Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.
COG4346 COG4346 5.37e-16 205 443 126 331
Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase [Posttranslational modification, protein turnover, chaperones].
pfam02366 PMT 8.76e-15 190 383 19 239
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ANU42918.1 1.00e-171 23 580 46 653
QQR07704.1 1.00e-171 23 580 46 653
QIA32159.1 3.21e-169 23 580 42 649
QBB67038.1 2.24e-155 40 580 74 752
ALP95330.1 4.46e-155 40 580 74 752

PDB Hits      help

has no PDB hit.

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
P9WN04 1.59e-25 175 578 72 521
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh) OX=83331 GN=pmt PE=3 SV=2
P9WN05 1.59e-25 175 578 72 521
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) OX=83332 GN=pmt PE=1 SV=2
L8F4Z2 2.13e-24 167 578 57 515
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Mycolicibacterium smegmatis (strain MKD8) OX=1214915 GN=pmt PE=3 SV=1
Q8NRZ6 2.96e-18 164 578 52 519
Probable dolichyl-phosphate-mannose--protein mannosyltransferase OS=Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) OX=196627 GN=pmt PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.969484 0.004992 0.025297 0.000031 0.000017 0.000169

TMHMM  Annotations      download full data without filtering help

start end
5 22
43 62
236 258
293 312
332 350
363 385
456 478
485 507
511 528
535 557