dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000002705_01556

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Species

Lineage

Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Acutalibacteraceae; UMGS856;

CAZyme ID

MGYG000002705_01556

CAZy Family

GH29

CAZyme Description

hypothetical protein

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
504		55774.56	5.5606

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000002705	2922707	MAG	Canada	North America

Gene Location

Start: 28317; End: 29831 Strand: +

No EC number prediction in MGYG000002705_01556.

Family	Start	End	Evalue	family coverage
GH29	40	271	2.3e-39	0.6040462427745664

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG3669	AfuC	6.01e-20	40	362	80	419	Alpha-L-fucosidase [Carbohydrate transport and metabolism].
pfam01120	Alpha_L_fucos	3.73e-13	40	271	110	326	Alpha-L-fucosidase.
smart00812	Alpha_L_fucos	8.90e-13	40	271	107	328	Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis.

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AYQ34472.1	4.33e-106	27	490	81	542
AXE18560.1	3.41e-105	27	430	81	491
AEI49018.1	6.77e-105	27	383	81	436
QMV17947.1	6.07e-101	27	438	93	489
ACO32076.1	1.87e-95	27	438	103	499

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
3GZA_A	2.58e-58	44	360	89	427	Crystalstructure of putative alpha-L-fucosidase (NP_812709.1) from BACTEROIDES THETAIOTAOMICRON VPI-5482 at 1.60 A resolution [Bacteroides thetaiotaomicron VPI-5482],3GZA_B Crystal structure of putative alpha-L-fucosidase (NP_812709.1) from BACTEROIDES THETAIOTAOMICRON VPI-5482 at 1.60 A resolution [Bacteroides thetaiotaomicron VPI-5482]
5K9H_A	4.30e-40	27	383	95	473	Crystalstructure of a glycoside hydrolase 29 family member from an unknown rumen bacterium [unidentified]
4ZRX_A	3.24e-38	40	360	101	445	Crystalstructure of a putative alpha-L-fucosidase (BACOVA_04357) from Bacteroides ovatus ATCC 8483 at 1.59 A resolution [Bacteroides ovatus ATCC 8483]
6TR3_A	2.53e-32	40	397	101	526	Ruminococcusgnavus GH29 fucosidase E1_10125 in complex with fucose [[Ruminococcus] gnavus E1]
6TR4_A	2.89e-31	40	397	101	526	Ruminococcusgnavus GH29 fucosidase E1_10125 D221A mutant in complex with fucose [[Ruminococcus] gnavus E1],6TR4_B Ruminococcus gnavus GH29 fucosidase E1_10125 D221A mutant in complex with fucose [[Ruminococcus] gnavus E1]

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
Q8GW72	9.51e-35	40	397	107	505	Alpha-L-fucosidase 1 OS=Arabidopsis thaliana OX=3702 GN=FUC1 PE=1 SV=2
Q7XUR3	7.33e-32	40	349	109	452	Putative alpha-L-fucosidase 1 OS=Oryza sativa subsp. japonica OX=39947 GN=Os04g0560400 PE=3 SV=2

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.993127	0.006751	0.000079	0.000022	0.000014	0.000030

There is no transmembrane helices in MGYG000002705_01556.