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CAZyme Information: MGYG000002994_00625

You are here: Home > Sequence: MGYG000002994_00625

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Megasphaera sp002319965
Lineage Bacteria; Firmicutes_C; Negativicutes; Veillonellales; Megasphaeraceae; Megasphaera; Megasphaera sp002319965
CAZyme ID MGYG000002994_00625
CAZy Family GT83
CAZyme Description Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
513 58409.01 9.1071
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000002994 2223689 MAG United States North America
Gene Location Start: 15909;  End: 17450  Strand: +

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000002994_00625.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GT83 2 479 1.7e-108 0.8888888888888888

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
PRK13279 arnT 7.58e-61 2 326 42 363
lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase.
COG1807 ArnT 3.45e-55 2 467 44 512
4-amino-4-deoxy-L-arabinose transferase or related glycosyltransferase of PMT family [Cell wall/membrane/envelope biogenesis].
pfam13231 PMT_2 2.46e-16 22 181 2 160
Dolichyl-phosphate-mannose-protein mannosyltransferase. This family contains members that are not captured by pfam02366.
pfam02366 PMT 2.13e-07 2 180 41 231
Dolichyl-phosphate-mannose-protein mannosyltransferase. This is a family of Dolichyl-phosphate-mannose-protein mannosyltransferase proteins EC:2.4.1.109. These proteins are responsible for O-linked glycosylation of proteins, they catalyze the reaction:- Dolichyl phosphate D-mannose + protein <=> dolichyl phosphate + O-D-mannosyl-protein. Also in this family is Drosophila rotated abdomen protein which is a putative mannosyltransferase. This family appears to be distantly related to pfam02516 (A Bateman pers. obs.). This family also contains sequences from ArnTs (4-amino-4-deoxy-L-arabinose lipid A transferase). They catalyze the addition of 4-amino-4-deoxy-l-arabinose (l-Ara4N) to the lipid A moiety of the lipopolysaccharide. This is a critical modification enabling bacteria (e.g. Escherichia coli and Salmonella typhimurium) to resist killing by antimicrobial peptides such as polymyxins. Members such as undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase are predicted to have 12 trans-membrane regions. The N-terminal portion of these proteins is hypothesized to have a conserved glycosylation activity which is shared between distantly related oligosaccharyltransferases ArnT and PglB families.
COG4745 COG4745 9.78e-07 14 328 58 403
Predicted membrane-bound mannosyltransferase [General function prediction only].

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
ALG43014.1 1.45e-316 1 508 46 553
AVO73572.1 2.40e-315 1 508 46 553
CCC73616.1 2.40e-315 1 508 46 553
AVO26253.1 2.29e-313 1 508 46 553
AXB81287.1 2.42e-301 1 506 46 551

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
5EZM_A 3.19e-49 2 474 68 542
CrystalStructure of ArnT from Cupriavidus metallidurans in the apo state [Cupriavidus metallidurans CH34],5F15_A Crystal Structure of ArnT from Cupriavidus metallidurans bound to Undecaprenyl phosphate [Cupriavidus metallidurans CH34]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q4K884 5.40e-44 2 503 74 576
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2 OS=Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) OX=220664 GN=arnT2 PE=3 SV=1
C5BDQ8 1.18e-42 2 452 41 494
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Edwardsiella ictaluri (strain 93-146) OX=634503 GN=arnT PE=3 SV=1
Q3KCB9 3.44e-40 2 449 41 485
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2 OS=Pseudomonas fluorescens (strain Pf0-1) OX=205922 GN=arnT2 PE=3 SV=1
A6V1N8 4.72e-40 3 321 42 360
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Pseudomonas aeruginosa (strain PA7) OX=381754 GN=arnT PE=3 SV=1
A1JPM4 6.91e-40 2 464 43 507
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase OS=Yersinia enterocolitica serotype O:8 / biotype 1B (strain NCTC 13174 / 8081) OX=393305 GN=arnT PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
1.000011 0.000011 0.000000 0.000000 0.000000 0.000000

TMHMM  Annotations      download full data without filtering help

start end
42 64
71 93
130 152
159 181
215 237
254 271
276 295
308 327
337 359
364 386
406 428