dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000003005_02234

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Basic Information help

Species

Lineage

Bacteria; Firmicutes_A; Clostridia; Oscillospirales; Ruminococcaceae; Ruminococcus;

CAZyme ID

MGYG000003005_02234

CAZy Family

GH5

CAZyme Description

Cellulase/esterase CelE

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
446		50493.66	4.1195

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003005	2620760	MAG	United States	North America

Gene Location

Start: 270; End: 1610 Strand: +

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000003005_02234.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
GH5	75	356	9.2e-93	0.9855072463768116

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
pfam00150	Cellulase	8.70e-45	65	323	5	237	Cellulase (glycosyl hydrolase family 5).
COG2730	BglC	4.31e-18	39	323	43	322	Aryl-phospho-beta-D-glucosidase BglC, GH1 family [Carbohydrate transport and metabolism].
cd14256	Dockerin_I	4.97e-11	391	440	3	54	Type I dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type I dockerins, which are responsible for anchoring a variety of enzymatic domains to the complex.
cd14254	Dockerin_II	2.54e-07	390	442	1	53	Type II dockerin repeat domain. Bacterial cohesin domains bind to a complementary protein domain named dockerin, and this interaction is required for the formation of the cellulosome, a cellulose-degrading complex. The cellulosome consists of scaffoldin, a noncatalytic scaffolding polypeptide, that comprises repeating cohesion modules and a single carbohydrate-binding module (CBM). Specific calcium-dependent interactions between cohesins and dockerins appear to be essential for cellulosome assembly. This subfamily represents type II dockerins, which are responsible for mediating attachment of the cellulosome complex to the bacterial cell wall.
pfam00404	Dockerin_1	1.46e-05	391	442	2	55	Dockerin type I repeat. The dockerin repeat is the binding partner of the cohesin domain pfam00963. The cohesin-dockerin interaction is the crucial interaction for complex formation in the cellulosome. The dockerin repeats, each bearing homology to the EF-hand calcium-binding loop bind calcium.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
CBK96759.1	2.39e-167	34	388	37	391
CBL35076.1	2.58e-164	35	388	28	381
ADL52801.1	7.32e-147	34	411	42	422
BAV13032.1	7.32e-147	34	411	42	422
ADL51185.1	1.15e-145	35	411	41	421

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6XRK_A	9.14e-71	39	381	23	370	GH5-4broad specificity endoglucanase from an uncultured bovine rumen ciliate [uncultured bovine rumen ciliate],6XRK_B GH5-4 broad specificity endoglucanase from an uncultured bovine rumen ciliate [uncultured bovine rumen ciliate]
6GL2_A	2.10e-60	33	379	7	336	Structureof ZgEngAGH5_4 wild type at 1.2 Angstrom resolution [Zobellia galactanivorans]
6GL0_A	2.70e-59	35	379	3	330	Structureof ZgEngAGH5_4 in complex with a cellotriose [Zobellia galactanivorans],6GL0_B Structure of ZgEngAGH5_4 in complex with a cellotriose [Zobellia galactanivorans],6GL0_C Structure of ZgEngAGH5_4 in complex with a cellotriose [Zobellia galactanivorans]
6MQ4_A	2.87e-57	35	356	7	314	ChainA, cellulase [Acetivibrio cellulolyticus]
5OYC_A	8.66e-57	30	379	37	390	GH5endo-xyloglucanase from Cellvibrio japonicus [Cellvibrio japonicus Ueda107],5OYC_B GH5 endo-xyloglucanase from Cellvibrio japonicus [Cellvibrio japonicus Ueda107],5OYD_A GH5 endo-xyloglucanase from Cellvibrio japonicus [Cellvibrio japonicus Ueda107],5OYD_B GH5 endo-xyloglucanase from Cellvibrio japonicus [Cellvibrio japonicus Ueda107],5OYE_A GH5 endo-xyloglucanase from Cellvibrio japonicus [Cellvibrio japonicus Ueda107],5OYE_B GH5 endo-xyloglucanase from Cellvibrio japonicus [Cellvibrio japonicus Ueda107]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
P23660	1.21e-54	26	355	13	327	Endoglucanase A OS=Ruminococcus albus OX=1264 GN=celA PE=1 SV=1
P28621	1.42e-54	35	356	37	339	Endoglucanase B OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=engB PE=3 SV=1
P28623	2.56e-54	35	356	38	337	Endoglucanase D OS=Clostridium cellulovorans (strain ATCC 35296 / DSM 3052 / OCM 3 / 743B) OX=573061 GN=engD PE=1 SV=2
P54937	1.95e-53	5	355	7	341	Endoglucanase A OS=Clostridium longisporum OX=1523 GN=celA PE=1 SV=1
A7LXT7	2.02e-53	35	356	145	473	Xyloglucan-specific endo-beta-1,4-glucanase BoGH5A OS=Bacteroides ovatus (strain ATCC 8483 / DSM 1896 / JCM 5824 / BCRC 10623 / CCUG 4943 / NCTC 11153) OX=411476 GN=BACOVA_02653 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.000240	0.999112	0.000165	0.000171	0.000150	0.000137

TMHMM Annotations download full data without filtering help

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