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CAZyme Information: MGYG000003014_01169

You are here: Home > Sequence: MGYG000003014_01169

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Actinomyces graevenitzii
Lineage Bacteria; Actinobacteriota; Actinomycetia; Actinomycetales; Actinomycetaceae; Actinomyces; Actinomyces graevenitzii
CAZyme ID MGYG000003014_01169
CAZy Family GH33
CAZyme Description hypothetical protein
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
755 MGYG000003014_30|CGC1 79728.77 7.8486
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003014 1770918 MAG United States North America
Gene Location Start: 7249;  End: 9516  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003014_01169.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH33 46 392 7.5e-77 0.935672514619883

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd15482 Sialidase_non-viral 1.17e-86 42 400 1 337
Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
COG4409 NanH 3.68e-32 31 403 251 657
Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis].
pfam13088 BNR_2 3.60e-11 66 381 1 278
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
pfam13859 BNR_3 4.54e-07 57 279 1 208
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
pfam10633 NPCBM_assoc 6.52e-05 419 490 3 75
NPCBM-associated, NEW3 domain of alpha-galactosidase. The English-language version of the first reference can be found on pages 388-399 of the above. This domain has been named NEW3 but its actual function is not known. It is found on proteins which are bacterial galactosidases. The domain is associated with the NPCBM family, pfam08305, a novel putative carbohydrate binding module found at the N-terminus of glycosyl hydrolases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
AZQ76181.1 5.17e-160 12 601 19 599
ANP28544.1 2.60e-149 29 595 41 597
ATH95829.1 3.83e-143 32 511 42 508
QRZ61396.1 2.32e-112 9 605 6 617
ALE04399.1 2.81e-112 39 625 45 675

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1EUT_A 6.61e-110 39 490 9 444
Sialidase,Large 68kd Form, Complexed With Galactose [Micromonospora viridifaciens],1EUU_A Sialidase Or Neuraminidase, Large 68kd Form [Micromonospora viridifaciens]
1WCQ_A 2.30e-109 39 490 5 440
Mutagenesisof the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_B Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_C Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens]
2BZD_A 4.52e-109 39 490 5 440
Galactoserecognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens],2BZD_B Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens],2BZD_C Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens]
1W8N_A 6.35e-109 39 490 5 440
Contributionof the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens. [Micromonospora viridifaciens],1W8O_A Contribution of the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens [Micromonospora viridifaciens]
2BER_A 1.76e-108 39 490 5 440
Y370GActive Site Mutant of the Sialidase from Micromonospora viridifaciens in complex with beta-Neu5Ac (sialic acid). [Micromonospora viridifaciens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q02834 1.14e-108 39 490 51 486
Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1
P29767 2.52e-14 55 414 395 837
Sialidase OS=Clostridium septicum OX=1504 PE=3 SV=1
P10481 1.49e-10 55 284 36 265
Sialidase OS=Clostridium perfringens OX=1502 GN=nanH PE=1 SV=1
Q27701 2.89e-09 165 386 513 729
Anhydrosialidase OS=Macrobdella decora OX=6405 PE=1 SV=1
P62575 9.77e-09 162 386 538 768
Sialidase A OS=Streptococcus pneumoniae OX=1313 GN=nanA PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.000557 0.998647 0.000205 0.000209 0.000182 0.000156

TMHMM  Annotations      download full data without filtering help

start end
721 743