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CAZyme Information: MGYG000003021_00623
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Pasteurellaceae; Haemophilus_D; | |||||||||||
| CAZyme ID | MGYG000003021_00623 | |||||||||||
| CAZy Family | GT19 | |||||||||||
| CAZyme Description | Lipid-A-disaccharide synthase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 53; End: 1213 Strand: + | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GT19 | 8 | 369 | 3.8e-139 | 0.9943502824858758 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| TIGR00215 | lpxB | 0.0 | 1 | 380 | 1 | 385 | lipid-A-disaccharide synthase. Lipid-A precursor biosynthesis producing lipid A disaccharide in a condensation reaction. transcribed as part of an operon including lpxA [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides] |
| COG0763 | LpxB | 0.0 | 6 | 383 | 2 | 381 | Lipid A disaccharide synthetase [Cell wall/membrane/envelope biogenesis]. |
| PRK00025 | lpxB | 0.0 | 5 | 384 | 1 | 378 | lipid-A-disaccharide synthase; Reviewed |
| pfam02684 | LpxB | 3.14e-177 | 8 | 377 | 1 | 371 | Lipid-A-disaccharide synthetase. This is a family of lipid-A-disaccharide synthetases, EC:2.4.2.128. These enzymes catalyze the reaction: UDP-2,3-bis(3-hydroxytetradecanoyl) glucosamine + 2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate <=> UDP + 2,3-bis(3-hydroxytetradecanoyl)-D-glucosaminyl-1,6 -beta-D-2,3-bis(3-hydroxytetradecanoyl)-beta-D-glucosaminyl 1-phosphate. These enzymes catalyze the fist disaccharide step in the synthesis of lipid-A-disaccharide. |
| PRK01021 | lpxB | 9.69e-46 | 5 | 340 | 226 | 566 | lipid-A-disaccharide synthase; Reviewed |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QOR25549.1 | 4.94e-270 | 1 | 386 | 1 | 389 |
| VEI30784.1 | 9.98e-270 | 1 | 386 | 1 | 389 |
| QOR16198.1 | 6.73e-268 | 1 | 386 | 1 | 389 |
| QOR08915.1 | 1.93e-267 | 1 | 386 | 1 | 389 |
| CBW15127.1 | 7.85e-267 | 1 | 386 | 1 | 389 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 5W8N_A | 7.16e-160 | 1 | 382 | 1 | 379 | LipidA Disaccharide Synthase (LpxB)-6 solubilizing mutations [Escherichia coli BL21(DE3)] |
| 5W8S_A | 1.44e-159 | 1 | 382 | 1 | 379 | LipidA Disaccharide Synthase (LpxB)-7 solubilizing mutations [Escherichia coli BL21(DE3)],5W8X_A Lipid A Disaccharide Synthase (LpxB)-7 solubilizing mutations-Bound to UDP [Escherichia coli BL21(DE3)] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| A5UD44 | 3.67e-218 | 1 | 382 | 1 | 385 | Lipid-A-disaccharide synthase OS=Haemophilus influenzae (strain PittEE) OX=374930 GN=lpxB PE=3 SV=1 |
| P45011 | 5.21e-218 | 1 | 382 | 1 | 385 | Lipid-A-disaccharide synthase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) OX=71421 GN=lpxB PE=3 SV=2 |
| Q4QLM6 | 4.27e-217 | 1 | 382 | 1 | 385 | Lipid-A-disaccharide synthase OS=Haemophilus influenzae (strain 86-028NP) OX=281310 GN=lpxB PE=3 SV=1 |
| A5UII8 | 2.46e-216 | 1 | 382 | 1 | 385 | Lipid-A-disaccharide synthase OS=Haemophilus influenzae (strain PittGG) OX=374931 GN=lpxB PE=3 SV=1 |
| Q65VI1 | 7.85e-210 | 1 | 382 | 8 | 392 | Lipid-A-disaccharide synthase OS=Mannheimia succiniciproducens (strain MBEL55E) OX=221988 GN=lpxB PE=3 SV=1 |
SignalP and Lipop Annotations help
This protein is predicted as OTHER
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 1.000028 | 0.000001 | 0.000000 | 0.000000 | 0.000000 | 0.000000 |