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CAZyme Information: MGYG000003132_01461

You are here: Home > Sequence: MGYG000003132_01461

Basic Information | Genomic context | Full Sequence | Enzyme annotations |  CAZy signature domains |  CDD domains | CAZyme hits | PDB hits | Swiss-Prot hits | SignalP and Lipop annotations | TMHMM annotations

Basic Information help

Species Dysgonomonas sp900556485
Lineage Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Dysgonomonadaceae; Dysgonomonas; Dysgonomonas sp900556485
CAZyme ID MGYG000003132_01461
CAZy Family GH33
CAZyme Description Sialidase
CAZyme Property
Protein Length CGC Molecular Weight Isoelectric Point
441 MGYG000003132_8|CGC2 50103.69 7.6394
Genome Property
Genome Assembly ID Genome Size Genome Type Country Continent
MGYG000003132 2983269 MAG United States North America
Gene Location Start: 79961;  End: 81286  Strand: -

Full Sequence      Download help

Enzyme Prediction      help

No EC number prediction in MGYG000003132_01461.

CAZyme Signature Domains help

Family Start End Evalue family coverage
GH33 43 420 9.5e-82 0.9298245614035088

CDD Domains      download full data without filtering help

Cdd ID Domain E-Value qStart qEnd sStart sEnd Domain Description
cd15482 Sialidase_non-viral 2.57e-81 39 427 1 334
Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases.
pfam13088 BNR_2 6.51e-25 63 413 1 280
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.
COG4409 NanH 8.68e-10 50 417 273 701
Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis].
pfam13859 BNR_3 0.007 63 283 9 174
BNR repeat-like domain. This family of proteins contains BNR-like repeats suggesting these proteins may act as sialidases.

CAZyme Hits      help

Hit ID E-Value Query Start Query End Hit Start Hit End
QGY44271.1 7.01e-192 37 434 41 438
QEC52363.1 1.11e-102 31 435 28 432
SDS88269.1 5.09e-68 34 440 66 414
SDS88228.1 2.40e-67 36 441 41 387
QEH41786.1 4.46e-66 38 431 35 366

PDB Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
1EUR_A 3.34e-37 47 433 20 359
Sialidase[Micromonospora viridifaciens],1EUS_A Sialidase Complexed With 2-Deoxy-2,3-Dehydro-N- Acetylneuraminic Acid [Micromonospora viridifaciens]
1EUT_A 8.89e-36 47 433 20 359
Sialidase,Large 68kd Form, Complexed With Galactose [Micromonospora viridifaciens],1EUU_A Sialidase Or Neuraminidase, Large 68kd Form [Micromonospora viridifaciens]
1W8N_A 1.18e-35 47 433 16 355
Contributionof the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens. [Micromonospora viridifaciens],1W8O_A Contribution of the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens [Micromonospora viridifaciens]
1WCQ_A 2.98e-35 47 433 16 355
Mutagenesisof the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_B Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_C Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens]
2BZD_A 5.54e-35 47 433 16 355
Galactoserecognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens],2BZD_B Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens],2BZD_C Galactose recognition by the carbohydrate-binding module of a bacterial sialidase. [Micromonospora viridifaciens]

Swiss-Prot Hits      download full data without filtering help

Hit ID E-Value Query Start Query End Hit Start Hit End Description
Q02834 6.48e-35 47 433 62 401
Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1
P31206 6.72e-22 19 418 158 528
Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2
P29767 3.84e-20 50 433 393 826
Sialidase OS=Clostridium septicum OX=1504 PE=3 SV=1
O35657 5.22e-19 49 418 68 390
Sialidase-1 OS=Mus musculus OX=10090 GN=Neu1 PE=1 SV=1
Q99519 7.36e-19 2 419 26 397
Sialidase-1 OS=Homo sapiens OX=9606 GN=NEU1 PE=1 SV=1

SignalP and Lipop Annotations help

This protein is predicted as SP

Other SP_Sec_SPI LIPO_Sec_SPII TAT_Tat_SPI TATLIP_Sec_SPII PILIN_Sec_SPIII
0.002742 0.996136 0.000371 0.000231 0.000230 0.000247

TMHMM  Annotations      download full data without filtering help

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