dbCAN-seq: a database of CAZyme sequence and annotation

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CAZyme Information: MGYG000003184_03574

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Basic Information help

Species

Mixta calida

Lineage

Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Mixta; Mixta calida

CAZyme ID

MGYG000003184_03574

CAZy Family

AA3

CAZyme Description

Oxygen-dependent choline dehydrogenase

CAZyme Property

Protein Length	CGC	Molecular Weight	Isoelectric Point
561	MGYG000003184_33\|CGC1	62807.84	6.8561

Genome Property

Genome Assembly ID	Genome Size	Genome Type	Country	Continent
MGYG000003184	4133670	MAG	United States	North America

Gene Location

Start: 3666; End: 5351 Strand: -

Full Sequence Download help

Enzyme Prediction help

No EC number prediction in MGYG000003184_03574.

CAZyme Signature Domains help

Family	Start	End	Evalue	family coverage
AA3	3	531	4.4e-166	0.9929577464788732

CDD Domains download full data without filtering help

Cdd ID	Domain	E-Value	qStart	qEnd	sStart	sEnd	Domain Description
COG2303	BetA	0.0	3	538	7	541	Choline dehydrogenase or related flavoprotein [Lipid transport and metabolism, General function prediction only].
PRK02106	PRK02106	0.0	1	551	3	552	choline dehydrogenase; Validated
TIGR01810	betA	0.0	5	536	1	532	choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli, Staphylococcus xylosus, and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified. [Cellular processes, Adaptations to atypical conditions]
pfam00732	GMC_oxred_N	1.88e-62	74	300	15	218	GMC oxidoreductase. This family of proteins bind FAD as a cofactor.
pfam05199	GMC_oxred_C	5.14e-46	392	526	3	143	GMC oxidoreductase. This domain found associated with pfam00732.

CAZyme Hits help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End
AWP09430.1	2.85e-183	3	545	19	565
ANI26486.1	5.75e-180	3	545	70	616
CAB3230510.1	4.50e-173	6	536	27	561
CAG5089487.1	3.91e-153	2	536	15	564
CAG5086058.1	5.88e-151	3	544	14	577

PDB Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
6ZH7_A	2.34e-85	2	541	6	571	ChainA, Fatty acid photodecarboxylase, chloroplastic [Chlorella variabilis],6ZH7_B Chain B, Fatty acid photodecarboxylase, chloroplastic [Chlorella variabilis]
6YRU_AAA	2.34e-85	2	541	6	571	ChainAAA, Fatty acid Photodecarboxylase [Chlorella variabilis],6YRV_AAA Chain AAA, Fatty acid Photodecarboxylase [Chlorella variabilis],6YRX_AAA Chain AAA, Fatty acid Photodecarboxylase [Chlorella variabilis],6YRZ_AAA Chain AAA, Fatty acid photodecarboxylase, chloroplastic [Chlorella variabilis]
6YS1_AAA	3.29e-85	2	541	6	571	ChainAAA, Fatty acid Photodecarboxylase [Chlorella variabilis]
5NCC_A	3.48e-85	2	541	22	587	Structureof Fatty acid Photodecarboxylase in complex with FAD and palmitic acid [Chlorella variabilis],5NCC_B Structure of Fatty acid Photodecarboxylase in complex with FAD and palmitic acid [Chlorella variabilis],5NCC_C Structure of Fatty acid Photodecarboxylase in complex with FAD and palmitic acid [Chlorella variabilis],5NCC_D Structure of Fatty acid Photodecarboxylase in complex with FAD and palmitic acid [Chlorella variabilis],5NCC_E Structure of Fatty acid Photodecarboxylase in complex with FAD and palmitic acid [Chlorella variabilis],5NCC_F Structure of Fatty acid Photodecarboxylase in complex with FAD and palmitic acid [Chlorella variabilis]
6YS2_AAA	4.61e-85	2	541	6	571	ChainAAA, Fatty acid Photodecarboxylase [Chlorella variabilis]

Swiss-Prot Hits download full data without filtering help

Hit ID	E-Value	Query Start	Query End	Hit Start	Hit End	Description
B4SHV9	3.97e-314	2	545	5	550	Oxygen-dependent choline dehydrogenase OS=Stenotrophomonas maltophilia (strain R551-3) OX=391008 GN=betA PE=3 SV=1
B2FQ89	1.14e-313	2	545	5	550	Oxygen-dependent choline dehydrogenase OS=Stenotrophomonas maltophilia (strain K279a) OX=522373 GN=betA PE=3 SV=1
Q9L4K0	3.02e-313	3	544	6	547	Oxygen-dependent choline dehydrogenase OS=Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) OX=290398 GN=betA PE=3 SV=1
Q4ZM63	2.93e-311	2	544	5	549	Oxygen-dependent choline dehydrogenase OS=Pseudomonas syringae pv. syringae (strain B728a) OX=205918 GN=betA PE=3 SV=1
Q48CM7	3.41e-310	2	544	5	549	Oxygen-dependent choline dehydrogenase OS=Pseudomonas savastanoi pv. phaseolicola (strain 1448A / Race 6) OX=264730 GN=betA PE=3 SV=1

SignalP and Lipop Annotations help

This protein is predicted as OTHER

Other	SP_Sec_SPI	LIPO_Sec_SPII	TAT_Tat_SPI	TATLIP_Sec_SPII	PILIN_Sec_SPIII
0.999989	0.000019	0.000001	0.000000	0.000000	0.000000

TMHMM Annotations help

There is no transmembrane helices in MGYG000003184_03574.