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CAZyme Information: MGYG000003301_00497
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Basic Information |
Genomic context |
Full Sequence |
Enzyme annotations |
CAZy signature domains |
CDD domains |
CAZyme hits |
PDB hits |
Swiss-Prot hits |
SignalP and Lipop annotations |
TMHMM annotations
Basic Information help
| Species | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Lineage | Bacteria; Bacteroidota; Bacteroidia; Bacteroidales; Bacteroidaceae; F0040; | |||||||||||
| CAZyme ID | MGYG000003301_00497 | |||||||||||
| CAZy Family | GH33 | |||||||||||
| CAZyme Description | Sialidase | |||||||||||
| CAZyme Property |
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| Genome Property |
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| Gene Location | Start: 503; End: 1828 Strand: - | |||||||||||
CAZyme Signature Domains help
| Family | Start | End | Evalue | family coverage |
|---|---|---|---|---|
| GH33 | 48 | 404 | 5.7e-43 | 0.9064327485380117 |
CDD Domains download full data without filtering help
| Cdd ID | Domain | E-Value | qStart | qEnd | sStart | sEnd | Domain Description |
|---|---|---|---|---|---|---|---|
| cd15482 | Sialidase_non-viral | 1.77e-58 | 45 | 407 | 10 | 330 | Non-viral sialidases. Sialidases or neuraminidases function to bind and hydrolyze terminal sialic acid residues from various glycoconjugates, they play vital roles in pathogenesis, bacterial nutrition and cellular interactions. They have a six-bladed, beta-propeller fold with the non-viral sialidases containing 2-5 Asp-box motifs (most commonly Ser/Thr-X-Asp-[X]-Gly-X-Thr- Trp/Phe). This CD includes eubacterial and eukaryotic sialidases. |
| COG4409 | NanH | 5.49e-04 | 48 | 185 | 274 | 430 | Neuraminidase (sialidase) [Carbohydrate transport and metabolism, Cell wall/membrane/envelope biogenesis]. |
CAZyme Hits help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End |
|---|---|---|---|---|---|
| QYR10380.1 | 8.75e-117 | 39 | 427 | 27 | 395 |
| ALO48969.1 | 3.69e-112 | 39 | 428 | 29 | 400 |
| QFQ12979.1 | 2.59e-107 | 39 | 428 | 23 | 398 |
| EFC70822.1 | 2.26e-103 | 2 | 428 | 3 | 403 |
| QFQ13500.1 | 3.46e-81 | 44 | 430 | 633 | 1010 |
PDB Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| 7LBU_A | 1.89e-17 | 16 | 402 | 67 | 415 | ChainA, Exo-alpha-sialidase [Cutibacterium acnes],7LBV_A Chain A, Exo-alpha-sialidase [Cutibacterium acnes] |
| 1EUR_A | 2.73e-16 | 45 | 412 | 21 | 353 | Sialidase[Micromonospora viridifaciens],1EUS_A Sialidase Complexed With 2-Deoxy-2,3-Dehydro-N- Acetylneuraminic Acid [Micromonospora viridifaciens] |
| 1EUT_A | 6.61e-16 | 45 | 412 | 21 | 353 | Sialidase,Large 68kd Form, Complexed With Galactose [Micromonospora viridifaciens],1EUU_A Sialidase Or Neuraminidase, Large 68kd Form [Micromonospora viridifaciens] |
| 1W8N_A | 1.55e-15 | 45 | 412 | 17 | 349 | Contributionof the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens. [Micromonospora viridifaciens],1W8O_A Contribution of the Active Site Aspartic Acid to Catalysis in the Bacterial Neuraminidase from Micromonospora viridifaciens [Micromonospora viridifaciens] |
| 1WCQ_A | 2.06e-15 | 45 | 412 | 17 | 349 | Mutagenesisof the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_B Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens],1WCQ_C Mutagenesis of the Nucleophilic Tyrosine in a Bacterial Sialidase to Phenylalanine. [Micromonospora viridifaciens] |
Swiss-Prot Hits download full data without filtering help
| Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
|---|---|---|---|---|---|---|
| Q02834 | 3.83e-15 | 45 | 412 | 63 | 395 | Sialidase OS=Micromonospora viridifaciens OX=1881 GN=nedA PE=1 SV=1 |
| P15698 | 3.67e-10 | 49 | 268 | 54 | 266 | Sialidase OS=Paeniclostridium sordellii OX=1505 PE=1 SV=1 |
| P29767 | 1.47e-08 | 45 | 400 | 391 | 809 | Sialidase OS=Clostridium septicum OX=1504 PE=3 SV=1 |
| O97859 | 1.53e-07 | 38 | 234 | 12 | 213 | Sialidase-3 OS=Bos taurus OX=9913 GN=NEU3 PE=1 SV=1 |
| P31206 | 2.44e-07 | 49 | 269 | 203 | 419 | Sialidase OS=Bacteroides fragilis (strain YCH46) OX=295405 GN=nanH PE=3 SV=2 |
SignalP and Lipop Annotations help
This protein is predicted as SP
| Other | SP_Sec_SPI | LIPO_Sec_SPII | TAT_Tat_SPI | TATLIP_Sec_SPII | PILIN_Sec_SPIII |
|---|---|---|---|---|---|
| 0.000596 | 0.998305 | 0.000433 | 0.000231 | 0.000196 | 0.000195 |